Evidence map›Paper›PMID 11751581›Full record

ArticleEMBO reports2002

Mapping and identification of essential gene functions on the X chromosome of Drosophila.

Annette Peter, Petra Schöttler, Meike Werner, Nicole Beinert, Gordon Dowe, Peter Burkert, Foteini Mourkioti, Lore Dentzer, Yuchun He, Peter Deak and 44 more

Open access · bronzeAbstract read
In one paragraph

Article in EMBO reports, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 119 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. iScience · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

54 authors at 18 institutions in 8 countries.

Annette PeterMax-Planck-Institut für Biophysikalische Chemie, Abt. Molekulare Entwicklungsbiologie, Am Fassberg, 37077 Göttingen, Germany.
Petra Schöttler
Meike Werner
Nicole Beinert
Gordon Dowe
Peter Burkert
Foteini Mourkioti
Lore Dentzer
Yuchun He
Peter Deak
Panayiotis V Benos
Melanie K Gatt
Lee Murphy
David Harris
Bart Barrell
Concepcion Ferraz
Sophie Vidal
Christine Brun
Jacques Demaille
Edouard Cadieu
Stephane Dreano
Stephanie Gloux
Valerie Lelaure
Stéphanie Mottier
Francis Galibert
Dana Borkova
Belen Miñana
Fotis C Kafatos
Slava Bolshakov
Inga Sidén-Kiamos
George Papagiannakis
Lefteris Spanos
Christos Louis
Encarnación Madueño
Beatriz de Pablos
Juan Modolell
Alain Bucheton
Debbie Callister
Lorna Campbell
Nadine S Henderson
Paul J McMillan
Cathy Salles
Evelyn Tait
Phillipe Valenti
Robert D C Saunders
Alain Billaud
Lior Pachter
Robert Klapper
Wilfried Janning
David M Glover
Michael Ashburner
Hugo J Bellen
Herbert Jäckle
Ulrich Schäfer
Max Planck Institute for Biophysical Chemistry · DECentre National de la Recherche Scientifique · FRUniversity of Dundee · GBEuropean Molecular Biology Laboratory · DECentro de Biología Molecular Severo Ochoa · ESFORTH Institute of Molecular Biology and Biotechnology · GRWellcome Sanger Institute · GBBaylor College of Medicine · USUniversity of Münster · DEWellcome Trust · GBBridge University · SSFondation Jean Dausset-CEPH · FRInstitut de Génétique Humaine · FRInstitute of Molecular Biology and Biotechnology · BGThe Open University · GBUniversité de Montpellier · FRUniversity of California, Berkeley · USUniversity of Cambridge · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Drosophila melanogaster genome consists of four chromosomes that contain 165 Mb of DNA, 120 Mb of which are euchromatic. The two Drosophila Genome Projects, in collaboration with Celera Genomics Systems, have sequenced the genome, complementing the previously established physical and genetic maps. In addition, the Berkeley Drosophila Genome Project has undertaken large-scale functional analysis based on mutagenesis by transposable P element insertions into autosomes. Here, we present a large-scale P element insertion screen for vital gene functions and a BAC tiling map for the X chromosome. A collection of 501 X-chromosomal P element insertion lines was used to map essential genes cytogenetically and to establish short sequence tags (STSs) linking the insertion sites to the genome. The distribution of the P element integration sites, the identified genes and transcription units as well as the expression patterns of the P-element-tagged enhancers is described and discussed.

Indexed as

Chromosome MappingX ChromosomeAnimalsChromosomes, Artificial, BacterialContig MappingDNA ProbesDNA Transposable ElementsDrosophila melanogasterFemaleGenes, EssentialGenes, InsectMaleMutagenesisDNA ProbesDNA Transposable Elements

Identifiers

PMID11751581
PMCPMC1083931
OpenAlexW2121600028

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.