ArticleInfection and immunity2002
Increased CD8(+)-T-cell expression and a type 2 cytokine pattern during the muscular phase of Trichinella infection in humans.
Article in Infection and immunity, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 51 citations in OpenAlex.
- Patients with Trichinella spiralis infection display unmodified antigen-specific immune response to SARS-CoV-2.Memorias do Instituto Oswaldo Cruz · 2025Article
- Effect of linex treatment on IFN-γ and IL-4 in mice infected with Trichinella.BMC infectious diseases · 2024Article
- Primary characterization of the immune responses in Tibetan pigs infected with Chinese Tibet isolate of Trichinella spiralis.BMC veterinary research · 2021Article
- Primary characterization of the immune response in pigs infected with Trichinella spiralis.Veterinary research · 2020Article
- Article
- Sex-associated protective effect of early bisphenol-A exposure during enteric infection with Trichinella spiralis in mice.PloS one · 2019Article
- The Anti-parasitic Effect of Probiotic BacteriaHelminthologia · 2018Article
- Effect of Muscle Strength byInternational journal of medical sciences · 2018Article
- Trichinella inflammatory myopathy: host or parasite strategy?Parasites & vectors · 2011Review
- Development of cellular immune response of mice to infection with low doses of Trichinella spiralis, Trichinella britovi and Trichinella pseudospiralis larvae.Parasitology research · 2011Article
- Infection of non-encapsulated species of Trichinella ameliorates experimental autoimmune encephalomyelitis involving suppression of Th17 and Th1 response.Parasitology research · 2010Article
- Immunity to Trichinella spiralis muscle infection.Veterinary parasitology · 2009Review
- Cell-mediated response at the muscle phase of Trichinella pseudospiralis and Trichinella spiralis infections.Parasitology research · 2006Article
- M-RNA Gene Expression of INF-Γ and IL-10 during Intestinal Phase ofIranian journal of parasitologyArticle
- Kinetics Evaluation of IgM and IgG Levels in the Mice Infected withIranian journal of parasitologyArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cell-mediated immunity during the muscular phase of Trichinella infection in humans was studied. Cell proliferation, the phenotypic changes in the T-cell population, and expression and production of cytokines were examined by using peripheral blood mononuclear cells (PBMC) collected at different times postinfection from 10 individuals who had acquired Trichinella spiralis and five individuals who had acquired Trichinella britovi in two distinct outbreaks. T. spiralis and T. britovi crude worm extracts induced proliferation of PBMC from T. spiralis- and T. britovi-infected donors. Cytokine gene expression showed a predominant type 2 pattern for the entire period of infection studied, although gamma interferon (IFN-gamma) was expressed. Interleukin-2 (IL-2), IL-5, IL-10, and IFN-gamma production was found in PBMC of all donors. There was a good correspondence between the cytokine expression and production patterns. Changes in PBMC composition, with a trend toward an increase in CD8(+) lymphocyte counts, were observed.
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Registered trials
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