ArticleEmerging infectious diseases
Clonal expansion of sequence type (ST-)5 and emergence of ST-7 in serogroup A meningococci, Africa.
Article in Emerging infectious diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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22 citing papers in PubMed.
- Invasive meningococcal disease in Shanghai, China from 1950 to 2016: implications for serogroup B vaccine implementation.Scientific reports · 2018Article
- Article
- Serogroup and Clonal Characterization of Czech Invasive Neisseria meningitidis Strains Isolated from 1971 to 2015.PloS one · 2016Article
- Article
- Complete Genome Sequence of Neisseria meningitidis Serogroup A Strain NMA510612, Isolated from a Patient with Bacterial Meningitis in China.Genome announcements · 2014Article
- Sequence, distribution and chromosomal context of class I and class II pilin genes of Neisseria meningitidis identified in whole genome sequences.BMC genomics · 2014Article
- Epidemiological changes in meningococcal meningitis in Niger from 2008 to 2011 and the impact of vaccination.BMC infectious diseases · 2013Article
- Phenotypic and genotypic characterization of meningococcal carriage and disease isolates in Burkina Faso after mass vaccination with a serogroup a conjugate vaccine.BMC infectious diseases · 2013Article
- Modeling the cost-effectiveness of the integrated disease surveillance and response (IDSR) system: meningitis in Burkina Faso.PloS one · 2010Article
- Characterization of serogroup A Neisseria meningitidis from invasive meningococcal disease cases in Canada between 1979 and 2006: Epidemiological links to returning travellers.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2008Article
- Serum antibody responses in Ethiopian meningitis patients infected with Neisseria meningitidis serogroup A sequence type 7.Clinical and vaccine immunology : CVI · 2007Article
- Clonal waves of Neisseria colonisation and disease in the African meningitis belt: eight- year longitudinal study in northern Ghana.PLoS medicine · 2007Article
- Meningococcal disease in South Africa, 1999-2002.Emerging infectious diseases · 2007Article
- New rapid diagnostic tests for Neisseria meningitidis serogroups A, W135, C, and Y.PLoS medicine · 2006Article
- Multiple-locus variable-number tandem repeat analysis of Neisseria meningitidis yields groupings similar to those obtained by multilocus sequence typing.Journal of clinical microbiology · 2006Article
- Characterization of Neisseria meningitidis isolates from recent outbreaks in Ethiopia and comparison with those recovered during the epidemic of 1988 to 1989.Journal of clinical microbiology · 2006Article
- Molecular epidemiology and emergence of worldwide epidemic clones of Neisseria meningitidis in Taiwan.BMC infectious diseases · 2006Article
- Molecular epidemiology of neisseria meningitidis isolated in the African Meningitis Belt between 1988 and 2003 shows dominance of sequence type 5 (ST-5) and ST-11 complexes.Journal of clinical microbiology · 2005Article
- Multilocus sequence typing: Data analysis in clinical microbiology and public health.Molecular biotechnology · 2005Review
- Molecular epidemiology of meningococci isolated in Niger in 2003 shows serogroup A sequence type (ST)-7 and serogroup W135 ST-11 or ST-2881 strains.Journal of clinical microbiology · 2005Article
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6 authors.
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Abstract
One hundred four serogroup A meningococci in our collection, isolated in Africa from 1988 to 1999, were characterized by multilocus sequence typing (MLST). Our results and data from the Internet indicate that sequence type 5 (ST-5) strains were responsible for most of African outbreaks and sporadic cases during this period. In 1995, a new clone, characterized by ST-7 sequence, emerged and was responsible for severe outbreaks in Chad (1998) and Sudan (1999). MLST and epidemiologic data indicate that ST-5 and ST-7 represent two virulent clones. These two STs, which belong to subgroup III, differ only in the pgm locus: allele pgm3 is characteristic for ST-5 and allele pgm19 for ST-7. Subgroup III strains were responsible for two pandemics in the 1960s and 1980s. Our data show that the third subgroup III pandemic has now reached Africa.
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