ArticleEnvironmental health perspectives2001
Wildlife as sentinels of human health effects in the Great Lakes--St. Lawrence basin.
Article in Environmental health perspectives, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 112 citations in OpenAlex.
- The street as transdisciplinary infrastructure: real world labs in One Urban Health-well-being corner shops in Québec, Canada.BMC global and public health · 2026Review
- Modified QuEChERS methodology for the analysis of OCs and PCBs in liver and its application in wild birds (white stork, red kite, and griffon vulture).Frontiers in veterinary science · 2026Article
- Sliding scales for assessing and communicating human and ecological risks and complexities for restoration, remediation crises, and decisions.Journal of risk research · 2024Article
- Clearance and persistence of Escherichia coli in the freshwater mussel Unio mancus.Scientific reports · 2022Article
- Combining ecological, eco-cultural, and environmental justice parameters to create Eco-EJ indicators to monitor cultural and environmental justices for diverse communities around contaminated sites.Environmental monitoring and assessment · 2022Article
- Article
- Genotoxicity in American kestrels in an agricultural landscape in the Baja California peninsula, Mexico.Environmental science and pollution research international · 2020Article
- Chemical contamination assessment in mangrove-lined Caribbean coastal systems using the oyster Crassostrea rhizophorae as biomonitor species.Environmental science and pollution research international · 2018Article
- Analysis of PFAAs in American alligators part 2: Potential dietary exposure of South Carolina hunters from recreationally harvested alligator meat.Journal of environmental sciences (China) · 2017Article
- Article
- Genotoxic effects of Roundup Full II® on lymphocytes of Chaetophractus villosus (Xenarthra, Mammalia): In vitro studies.PloS one · 2017Article
- Erythrocyte micronucleus cytome assay of 17 wild bird species from the central Monte desert, Argentina.Environmental science and pollution research international · 2016Article
- Article
- Environmental Assessment for Sustainability and Resiliency for Ecological and Human Health.Journal of environmental studies (Northborough, Mass.) · 2015Article
- Complexity of bioindicator selection for ecological, human, and cultural health: Chinook salmon and red knot as case studies.Environmental monitoring and assessment · 2015Article
- Effect of pre-fixation delay and freezing on mink testicular endpoints for environmental research.PloS one · 2015Article
- The concentration of manganese, iron and strontium in bone of red fox Vulpes vulpes (L. 1758).Biological trace element research · 2013Article
- Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses.Endocrine reviews · 2012Review
- Anaemia, hypothyroidism and immune suppression associated with polychlorinated biphenyl exposure in bottlenose dolphins (Tursiops truncatus).Proceedings. Biological sciences · 2012Article
- An overview of the effects of dioxins and dioxin-like compounds on vertebrates, as documented in human and ecological epidemiology.Journal of environmental science and health. Part C, Environmental carcinogenesis & ecotoxicology reviews · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is no existing formal, long-term program for gathering evidence of the incidence and severity of the health effects of toxic substances in wildlife. However, research-based studies of bald eagles, herring gulls, night herons, tree swallows, snapping turtles, mink, and beluga over the past 30 years have revealed a broad spectrum of health effects in the Great Lakes-St. Lawrence basin including thyroid and other endocrine disorders, metabolic diseases, altered immune function, reproductive impairment, developmental toxicity, genotoxicity, and cancer. These effects occurred most often and were most severe in the most contaminated sites (Green Bay, Saginaw Bay, Lake Ontario, the St. Lawrence estuary, and more recently, Lake Erie), some of which are International Joint Commission-designated Areas of Concern (AOCs). In all cases, a strong argument can be made for an environmental etiology, and in many cases for the involvement of persistent organic pollutants, particularly polychlorinated biphenyls, polychlorinated dibenzo-(italic)p(/italic)-dioxins, and polycyclic aromatic hydrocarbons. For some, the association with particular contaminants is consistent with controlled studies, and in some, dose-response relationships were documented. The biologic significance of these health impairments to the affected species is currently unclear, but they resemble those observed with increased incidence in human subpopulations in one or more AOCs. Formalizing health effects monitoring of sentinel wildlife species by the parties to the Canada-USA Great Lakes Water Quality Agreement is required. This would facilitate the optimal use of sentinel wildlife health data in a larger, epidemiologic weight-of-evidence context upon which to base decisions and policies regarding the effects of chemical exposures on human populations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.