ArticlePlant physiology2001
Arabidopsis RTM1 and RTM2 genes function in phloem to restrict long-distance movement of tobacco etch virus.
Article in Plant physiology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.
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Who cites it
69 citing papers in PubMed, 168 citations in OpenAlex.
- The multidimensional significance of virus-host protein interactions and their implications in the antiviral defense of plants.Stress biology · 2026Review
- Durable Management of Plant Viruses: Insights into Host Resistance and Tolerance Mechanisms.Biology · 2026Review
- Regulatory DNA Sequences Controlling Gene Expression in Leaf Phloem Cells.Methods in molecular biology (Clifton, N.J.) · 2026Review
- Live-Cell Imaging of Fluorescently-Tagged Phloem Proteins with Confocal Microscopy.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Viral Systemic Movement Is Enhanced by Alteration of a Structural Phloem Protein by the Insect Vector.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Developmental landscape and asymmetric gene expression in the leaf vasculature ofHorticulture research · 2025Article
- Companion cell mediates wound-stimulated leaf-to-leaf electrical signaling.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Natural and Engineered Resistance Mechanisms in Plants against Phytoviruses.Pathogens (Basel, Switzerland) · 2023Review
- Transcriptome Dynamics inViruses · 2023Article
- Identification and Functional Analyses of Host Proteins Interacting with the P3a Protein of Brassica Yellows Virus.Biology · 2023Article
- Transcription factor NTL9 negatively regulates Arabidopsis vascular cambium development during stem secondary growth.Plant physiology · 2022Article
- Plantago asiatica mosaic virus: An emerging plant virus causing necrosis in lilies and a new model RNA virus for molecular research.Molecular plant pathology · 2022Review
- Effect of cultivar and temperature on the synergistic interaction between panicum mosaic virus and satellite panicum mosaic virus in switchgrass.Archives of virology · 2022Article
- Review
- SLI1 confers broad-spectrum resistance to phloem-feeding insects.Plant, cell & environment · 2021Article
- The mFrontiers in microbiology · 2021Article
- Genome-Wide Identification ofFrontiers in plant science · 2021Article
- Review
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- Host factors against plant viruses.Molecular plant pathology · 2019Review
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
Restriction of long-distance movement of tobacco etch virus (TEV) in Arabidopsis ecotype Col-0 plants requires the function of at least three genes: RTM1 (restricted TEV movement 1), RTM2, and RTM3. The mechanism of TEV movement restriction remains poorly understood, although it does not involve a hypersensitive response or systemic acquired resistance. A functional characterization of RTM1 and RTM2 was done. The RTM1 protein was found to be soluble with the potential to form self-interacting complexes. The regulatory regions of both the RTM1 and RTM2 genes were analyzed using reporter constructs. The regulatory sequences from both genes directed expression of beta-glucuronidase exclusively in phloem-associated cells. Translational fusion proteins containing the green fluorescent protein and RTM1 or RTM2 localized to sieve elements when expressed from their native regulatory sequences. Thus, components of the RTM system may function within phloem, and sieve elements in particular, to restrict TEV long-distance movement.
Indexed as
Identifiers
11743111PMC133571W2154722797What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.