ArticleJournal of bacteriology2002
Dynamics of genome architecture in Rhizobium sp. strain NGR234.
Article in Journal of bacteriology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 74 citations in OpenAlex.
- Article
- A dicentric bacterial chromosome requires XerC/D site-specific recombinases for resolution.Current biology : CB · 2022Article
- Prediction and identification of recurrent genomic rearrangements that generate chimeric chromosomes inProceedings of the National Academy of Sciences of the United States of America · 2019Article
- The complete replicons of 16 Ensifer meliloti strains offer insights into intra- and inter-replicon gene transfer, transposon-associated loci, and repeat elements.Microbial genomics · 2018Article
- Article
- High-quality draft genome sequence ofStandards in genomic sciences · 2017Article
- Genomic studies of nitrogen-fixing rhizobial strains from Phaseolus vulgaris seeds and nodules.BMC genomics · 2016Article
- The repABC Plasmids with Quorum-Regulated Transfer Systems in Members of the Rhizobiales Divide into Two Structurally and Separately Evolving Groups.Genome biology and evolution · 2015Article
- Genomic characterization of Sinorhizobium meliloti AK21, a wild isolate from the Aral Sea Region.SpringerPlus · 2015Article
- The detection of inherent homologous recombination between repeat sequences in H. pylori 26695 by the PCR-based method.Current microbiology · 2014Article
- Characterization of Rhizobium grahamii extrachromosomal replicons and their transfer among rhizobia.BMC microbiology · 2014Article
- Ecological dynamics and complex interactions of Agrobacterium megaplasmids.Frontiers in plant science · 2014Review
- Functional conservation of the capacity for ent-kaurene biosynthesis and an associated operon in certain rhizobia.Journal of bacteriology · 2014Article
- Diversity of culturable bacteria including Pantoea in wild mosquito Aedes albopictus.BMC microbiology · 2013Article
- The conjugative plasmid of a bean-nodulating Sinorhizobium fredii strain is assembled from sequences of two Rhizobium plasmids and the chromosome of a Sinorhizobium strain.BMC microbiology · 2011Article
- Plasmids with a chromosome-like role in rhizobia.Journal of bacteriology · 2011Article
- Mechanism of chromosomal transfer of Enterococcus faecalis pathogenicity island, capsule, antimicrobial resistance, and other traits.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Genetic and metabolic divergence within a Rhizobium leguminosarum bv. trifolii population recovered from clover nodules.Applied and environmental microbiology · 2010Article
- Recovery of nonpathogenic mutant bacteria from tumors caused by several Agrobacterium tumefaciens strains: a frequent event?Applied and environmental microbiology · 2009Article
- Application of physical and genetic map of Rhizobium leguminosarum bv. trifolii TA1 to comparison of three closely related rhizobial genomes.Molecular genetics and genomics : MGG · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacterial genomes are usually partitioned in several replicons, which are dynamic structures prone to mutation and genomic rearrangements, thus contributing to genome evolution. Nevertheless, much remains to be learned about the origins and dynamics of the formation of bacterial alternative genomic states and their possible biological consequences. To address these issues, we have studied the dynamics of the genome architecture in Rhizobium sp. strain NGR234 and analyzed its biological significance. NGR234 genome consists of three replicons: the symbiotic plasmid pNGR234a (536,165 bp), the megaplasmid pNGR234b (>2,000 kb), and the chromosome (>3,700 kb). Here we report that genome analyses of cell siblings showed the occurrence of large-scale DNA rearrangements consisting of cointegrations and excisions between the three replicons. As a result, four new genomic architectures have emerged. Three consisted of the cointegrates between two replicons: chromosome-pNGR234a, chromosome-pNGR234b, and pNGR234a-pNGR234b. The other consisted of a cointegrate of the three replicons (chromosome-pNGR234a-pNGR234b). Cointegration and excision of pNGR234a with either the chromosome or pNGR234b were studied and found to proceed via a Campbell-type mechanism, mediated by insertion sequence elements. We provide evidence showing that changes in the genome architecture did not alter the growth and symbiotic proficiency of Rhizobium derivatives.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.