ArticleJournal of bacteriology2002
The lytic enzyme of bacteriophage PRD1 is associated with the viral membrane.
Article in Journal of bacteriology, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 56 citations in OpenAlex.
- CRISPR spacers reveal diverse and abundant Thermococcales viruses in hydrothermal vents.Research square · 2026Article
- Jorvik: A membrane-containing phage that will likely found a new family within Vinavirales.iScience · 2023Article
- Isolation, biological and whole genome characteristics of a Proteus mirabilis bacteriophage strain.BMC microbiology · 2023Article
- Bacteriophage therapy as an alternative biocontrol against emerging multidrug resistantSaudi journal of biological sciences · 2022Article
- Indirect Selection against Antibiotic Resistance via Specialized Plasmid-Dependent Bacteriophages.Microorganisms · 2021Article
- Bacteriophage GC1, a Novel Tectivirus Infecting Gluconobacter Cerinus, an Acetic Acid Bacterium Associated with Wine-Making.Viruses · 2018Article
- Bacteriophage-encoded virion-associated enzymes to overcome the carbohydrate barriers during the infection process.Applied microbiology and biotechnology · 2017Review
- Joining the in vitro immunization of alpaca lymphocytes and phage display: rapid and cost effective pipeline for sdAb synthesis.Microbial cell factories · 2017Article
- Bacteriophages and phage-derived proteins--application approaches.Current medicinal chemistry · 2015Review
- Inhibition of biofilm formation by T7 bacteriophages producing quorum-quenching enzymes.Applied and environmental microbiology · 2014Article
- Molecular aspects and comparative genomics of bacteriophage endolysins.Journal of virology · 2013Article
- A peptidoglycan hydrolase motif within the mycobacteriophage TM4 tape measure protein promotes efficient infection of stationary phase cells.Molecular microbiology · 2006Article
- The entry mechanism of membrane-containing phage Bam35 infecting Bacillus thuringiensis.Journal of bacteriology · 2006Article
- The Holin protein of bacteriophage PRD1 forms a pore for small-molecule and endolysin translocation.Journal of bacteriology · 2005Article
- Phage P68 virion-associated protein 17 displays activity against clinical isolates of Staphylococcus aureus.Antimicrobial agents and chemotherapy · 2005Article
- The linear double-stranded DNA of phage Bam35 enters lysogenic host cells, but the late phage functions are suppressed.Journal of bacteriology · 2005Article
- Penetration of membrane-containing double-stranded-DNA bacteriophage PM2 into Pseudoalteromonas hosts.Journal of bacteriology · 2004Article
- Bacteriophage Tuc2009 encodes a tail-associated cell wall-degrading activity.Journal of bacteriology · 2004Article
- The tailless icosahedral membrane virus PRD1 localizes the proteins involved in genome packaging and injection at a unique vertex.Journal of virology · 2003Article
- The unique vertex of bacterial virus PRD1 is connected to the viral internal membrane.Journal of virology · 2003Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bacteriophage PRD1 encodes two proteins (P7 and P15) that are associated with a muralytic activity. Protein P15 is a soluble beta-1,4-N-acetylmuramidase that causes phage-induced host cell lysis. We demonstrate here that P15 is also a structural component of the PRD1 virion and that it is connected to the phage membrane. Small viral membrane proteins P20 and P22 modulate incorporation of P15 into the virion and may connect it to the phage membrane. The principal muralytic protein involved in PRD1 DNA entry seems to be the putative lytic transglycosylase protein P7, as the absence of protein P15 did not delay initiation of phage DNA replication in the virus-host system used. The incorporation of two different lytic enzymes into virions may reflect the broad host range of bacteriophage PRD1.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.