ArticleThe Biochemical journal2001
Identification of nucleolin as a new L-selectin ligand.
Article in The Biochemical journal, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 56 citations in OpenAlex.
- RNA-binding proteins as therapeutic targets in cancer.RNA biology · 2025Review
- Article
- Tumor diagnosis using carbon-based quantum dots: Detection based on the hallmarks of cancer.Bioactive materials · 2024Review
- Nucleolin mediates the binding of cancer cells to L-selectin under conditions of lymphodynamic shear stress.American journal of physiology. Cell physiology · 2020Article
- Involvement of nuclear protein C23 in activation of EGFR signaling in cervical cancer.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016Article
- Cell surface nucleolin interacts with CXCR4 receptor via the 212 c-terminal portion.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015Article
- The lectin-binding pattern of nucleolin and its interaction with endogenous galectin-3.Cellular & molecular biology letters · 2014Article
- Cell surface nucleolin is crucial in the activation of the CXCL12/CXCR4 signaling pathway.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2014Article
- The pseudopeptide HB-19 binds to cell surface nucleolin and inhibits angiogenesis.Vascular cell · 2012Article
- Nucleolin mediates the antiangiogenesis effect of the pseudopeptide N6L.BMC cell biology · 2012Article
- Article
- Surface expressed nucleolin is constantly induced in tumor cells to mediate calcium-dependent ligand internalization.PloS one · 2010Article
- Targeting surface nucleolin with a multivalent pseudopeptide delays development of spontaneous melanoma in RET transgenic mice.BMC cancer · 2010Article
- Induction of apoptosis with cisplatin enhances calcium oxalate crystal adherence to inner medullary collecting duct cells.Urological research · 2010Article
- Differential secreted proteome approach in murine model for candidate biomarker discovery in colon cancer.Journal of proteome research · 2009Article
- The new face of nucleolin in human melanoma.Cancer immunology, immunotherapy : CII · 2009Article
- Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer.Experimental and molecular pathology · 2009Review
- Article
- Cell-surface nucleolin is a signal transducing P-selectin binding protein for human colon carcinoma cells.Experimental cell research · 2008Article
- Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Apart from leucocyte-endothelial interactions, the adhesion molecule L-selectin mediates the homotypic adhesion of leucocytes during recruitment at sites of acute inflammation, as well as intercellular adhesion of haematopoietic progenitor cells during haematopoiesis. There is evidence that, in addition to P-selectin glycoprotein ligand-1, other as-yet-unidentified proteins function as L-selectin ligands on human leucocytes and haematopoietic progenitor cells. In the present study, we show: (i) by affinity chromatography on L-selectin-agarose; (ii) by protein identification using MS; and (iii) by covalent cell-surface labelling with sulphosuccinimidyl-2-(biotinamido)ethyl-1,3-dithiopropionate that the multifunctional nuclear protein nucleolin is partly exposed on the cell surface, and is a ligand of L-selectin in human leucocytes and haematopoietic progenitor cells.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.