ArticleGenetics2001
Expanding the diversity of the IS630-Tc1-mariner superfamily: discovery of a unique DD37E transposon and reclassification of the DD37D and DD39D transposons.
Article in Genetics, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
65 citing papers in PubMed, 142 citations in OpenAlex.
- Evidence for dual pathways of Tc1/mariner domestication in Drosophila.BMC biology · 2026Article
- Evolutionary History of the DD41D Family of Tc1/Mariner Transposons in Two Mayetiola Species.Biochemical genetics · 2025Article
- Discovery of the first Tn630 member and the closest homolog of IS630 from viruses.Scientific reports · 2024Article
- Active in vivo translocation of the Methanosarcina mazei Gö1 Casposon.Nucleic acids research · 2023Article
- maT and mosquito transposons in cnidarians: evolutionary history and intraspecific differences.Functional & integrative genomics · 2023Article
- Article
- The first discovery of Tc1 transposons in yeast.Frontiers in microbiology · 2023Article
- Article
- Revisiting theBiology · 2022Article
- Genome-wide characterization of Mariner-like transposons and their derived MITEs in the Whitefly Bemisia tabaci (Hemiptera: Aleyrodidae).G3 (Bethesda, Md.) · 2021Article
- Prokaryotic and Eukaryotic Horizontal Transfer ofBiology · 2021Article
- Diversity and Evolution ofBiology · 2021Article
- Characterization of Mariner transposons in seven species of Rhus gall aphids.Scientific reports · 2021Article
- Jumping Ahead withViruses · 2021Review
- Distribution of Merlin in eukaryotes and first report of DNA transposons in kinetoplastid protists.PloS one · 2021Article
- The Tc1-like elements with the spliceosomal introns in mollusk genomes.Molecular genetics and genomics : MGG · 2020Article
- The genomic survey of Tc1-like elements in the silkworm microsporidia Nosema bombycis.Acta parasitologica · 2020Article
- Traveler, a New DD35E Family of Tc1/Mariner Transposons, Invaded Vertebrates Very Recently.Genome biology and evolution · 2020Article
- Phylogenetic analysis of theMobile DNA · 2020Article
- Evolution ofMobile DNA · 2020Article
5 more citing papers are in PubMed but not listed here.
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
A novel transposon named ITmD37E was discovered in a wide range of mosquito species. Sequence analysis of multiple copies in three Aedes species showed similar terminal inverted repeats and common putative TA target site duplications. The ITmD37E transposases contain a conserved DD37E catalytic motif, which is unique among reported transposons of the IS630-Tc1-mariner superfamily. Sequence comparisons and phylogenetic analyses suggest that ITmD37E forms a novel family distinct from the widely distributed Tc1 (DD34E), mariner (DD34D), and pogo (DDxD) families in the IS630-Tc1-mariner superfamily. The inclusion in the phylogenetic analysis of recently reported transposons and transposons uncovered in our database survey provided revisions to previous classifications and identified two additional families, ITmD37D and ITmD39D, which contain DD37D and DD39D motifs, respectively. The above expansion and reorganization may open the doors to the discovery of related transposons in a broad range of organisms and help illustrate the evolution and structure-function relationships among these distinct transposases in the IS630-Tc1-mariner superfamily. The presence of intact open reading frames and highly similar copies in some of the newly characterized transposons suggests recent transposition. Studies of these novel families may add to the limited repertoire of transgenesis and mutagenesis tools for a wide range of organisms, including the medically important mosquitoes.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.