Evidence map›Paper›PMID 11724855›Full record

ArticleJournal of clinical microbiology2001

Multidrug-resistant Trichosporon asahii infection of nongranulocytopenic patients in three intensive care units.

D G Wolf, R Falk, M Hacham, B Theelen, T Boekhout, G Scorzetti, M Shapiro, C Block, I F Salkin, I Polacheck

Open access · greenAbstract readCase Reports
In one paragraph

Article in Journal of clinical microbiology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it, 140 citations in OpenAlex.

  1. Epidemiological study ofEpidemiology and infection · 2020
    Pooled it
  2. Article
  3. Article
  4. Future microbiology · 2025
    Review
  5. Article
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  7. Article
  8. Article
  9. Article
  10. Article
  11. Strain Typing ofJournal of laboratory physicians · 2021
    Article
  12. Urinary Tract Infections Caused by Fluconazole-ResistantOpen forum infectious diseases · 2020
    Article
  13. Article
  14. Article
  15. Invasive Infections Due toJournal of clinical microbiology · 2019
    Article
  16. BMJ case reports · 2018
    Article
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

D G WolfDepartment of Clinical Microbiology and Infectious Diseases, The Hebrew University-Hadassah Medical Center, Jerusalem, Israel.
R Falk
M Hacham
B Theelen
T Boekhout
G Scorzetti
M Shapiro
C Block
I F Salkin
I Polacheck
Hadassah Medical Center · ILNew York State Department of Health · USUniversity of Miami · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Trichosporon asahii (Trichosporon beigelii) infections are rare but have been associated with a wide spectrum of clinical manifestations, ranging from superficial involvement in immunocompetent individuals to severe systemic disease in immunocompromised patients. We report on the recent recovery of T. asahii isolates with reduced susceptibility in vitro to amphotericin B (AMB), flucytosine, and azoles from six nongranulocytopenic patients who exhibited risk factors and who developed either superficial infections (four individuals) or invasive infections (two individuals) while in intensive care units. The latter two patients responded clinically and microbiologically to AMB treatment. All six isolates were closely related according to random amplified polymorphic DNA studies and showed 71% similarity by amplified fragment length polymorphism analysis, suggesting a common nosocomial origin. We also review the literature pertaining to T. asahii infections and discuss the salient characteristics of this fungus and recent taxonomic proposals for the genus.

Indexed as

Drug Resistance, Multiple, FungalIntensive Care UnitsAgedAged, 80 and overAgranulocytosisAntifungal AgentsDNA, BacterialFemaleHumansMaleMicrobial Sensitivity TestsMiddle AgedMycosesPolymorphism, Restriction Fragment LengthRandom Amplified Polymorphic DNA TechniqueTrichosporonAntifungal AgentsDNA, Bacterial

Identifiers

PMID11724855
PMCPMC88559
OpenAlexW2165212204

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.