ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2001
Temporal contrast adaptation in salamander bipolar cells.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 82 papers.
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Who cites it
82 citing papers in PubMed.
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- Direct comparison reveals algorithmic similarities in fly and mouse visual motion detection.iScience · 2023Article
- Rapid adaptation of primate LGN neurons to drifting grating stimulation.Journal of neurophysiology · 2023Article
- Enhancing the dark side: asymmetric gain of cone photoreceptors underpins their discrimination of visual scenes based on skewness.The Journal of physiology · 2022Article
- Nonlinear spatial integration in retinal bipolar cells shapes the encoding of artificial and natural stimuli.Neuron · 2021Article
- GABAeLife · 2021Article
- Linear and nonlinear chromatic integration in the mouse retina.Nature communications · 2021Article
- What the salamander eye has been telling the vision scientist's brain.Seminars in cell & developmental biology · 2020Review
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- A minimal synaptic model for direction selective neurons in Drosophila.Journal of vision · 2020Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
1 author.
Funding
Abstract
This work investigates how the light responses of salamander bipolar cells adapt to changes in temporal contrast: changes in the depth of the temporal fluctuations in light intensity about the mean. Contrast affected the sensitivity of bipolar cells but not of photoreceptors or horizontal cells, suggesting that adaptation occurred in signal transfer from photoreceptors to bipolars. This suggestion was confirmed by recording from photoreceptor-bipolar pairs and observing a direct dependence of the gain of signal transfer on the contrast of the light input. After an increase in contrast, the onset of adaptation in the bipolar cell had a time constant of 1-2 sec, similar to a fast component of contrast adaptation in the light responses of retinal ganglion cells (Kim and Rieke, 2001). Contrast adaptation was mediated by processes in the dendrites of both on and off bipolars. The functional properties of adaptation differed for the two bipolar types, however, with contrast having a much more pronounced effect on the kinetics of the responses of off cells than on cells.
Indexed as
Identifiers
11717378PMC6763932What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.