ArticleJournal of bacteriology2001
CheR- and CheB-dependent chemosensory adaptation system of Rhodobacter sphaeroides.
Article in Journal of bacteriology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 39 citations in OpenAlex.
- TheJournal of bacteriology · 2026Article
- Long-read methylome analysis of Oleidesulfovibrio alaskensis G20 biofilm under copper stress.Scientific reports · 2025Article
- Mechanism of Signalling and Adaptation through theInternational journal of molecular sciences · 2019Article
- Light-controlled motility in prokaryotes and the problem of directional light perception.FEMS microbiology reviews · 2017Review
- (1)H, (13)C and (15)N resonance assignments for the response regulator CheY3 from Rhodobacter sphaeroides.Biomolecular NMR assignments · 2016Article
- In Rhodobacter sphaeroides, chemotactic operon 1 regulates rotation of the flagellar system 2.Journal of bacteriology · 2011Article
- Feedback control architecture and the bacterial chemotaxis network.PLoS computational biology · 2011Article
- Signal processing in complex chemotaxis pathways.Nature reviews. Microbiology · 2011Review
- Modeling chemotaxis reveals the role of reversed phosphotransfer and a bi-functional kinase-phosphatase.PLoS computational biology · 2010Article
- Spatial organization in bacterial chemotaxis.The EMBO journal · 2010Review
- Using structural information to change the phosphotransfer specificity of a two-component chemotaxis signalling complex.PLoS biology · 2010Article
- Deciphering chemotaxis pathways using cross species comparisons.BMC systems biology · 2010Article
- Characterization of the Thermotoga maritima chemotaxis methylation system that lacks pentapeptide-dependent methyltransferase CheR:MCP tethering.Molecular microbiology · 2007Article
- Two chemosensory operons of Rhodobacter sphaeroides are regulated independently by sigma 28 and sigma 54.Journal of bacteriology · 2006Article
- Role of CheB and CheR in the complex chemotactic and aerotactic pathway of Azospirillum brasilense.Journal of bacteriology · 2006Article
- Differential localization of Mre proteins with PBP2 in Rhodobacter sphaeroides.Journal of bacteriology · 2006Article
- Localization of MreB in Rhodobacter sphaeroides under conditions causing changes in cell shape and membrane structure.Journal of bacteriology · 2005Article
- Diversity in chemotaxis mechanisms among the bacteria and archaea.Microbiology and molecular biology reviews : MMBR · 2004Review
- Polar localization of CheA2 in Rhodobacter sphaeroides requires specific Che homologs.Journal of bacteriology · 2003Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rhodobacter sphaeroides has multiple homologues of most of the Escherichia coli chemotaxis genes, organized in three major operons and other, unlinked, loci. These include cheA(1) and cheR(1) (che Op(1)) and cheA(2), cheR(2), and cheB(1) (che Op(2)). In-frame deletions of these cheR and cheB homologues were constructed and the chemosensory behaviour of the resultant mutants examined on swarm plates and in tethered cell assays. Under the conditions tested, CheR(2) and CheB(1) were essential for normal chemotaxis, whereas CheR(1) was not. cheR(2) and cheB(1), but not cheR(1), were also able to complement the equivalent E. coli mutants. However, none of the proteins were required for the correct polar localization of the chemoreceptor McpG in R. sphaeroides. In E. coli, CheR binds to the NWETF motif on the high-abundance receptors, allowing methylation of both high- and low-abundance receptors. This motif is not contained on any R. sphaeroides chemoreceptors thus far identified, although 2 of the 13 putative chemoreceptors, McpA and TlpT, do have similar sequences. This suggests that CheR(2) either interacts with the NWETF motif of E. coli methyl-accepting chemotaxis proteins (MCPs), even though its native motif may be slightly different, or with another conserved region of the MCPs. Methanol release measurements show that R. sphaeroides has an adaptation system that is different from that of Bacillus subtilis and E. coli, with methanol release measurable on the addition of attractant but not on its removal. Intriguingly, CheA(2), but not CheA(1), is able to phosphorylate CheB(1), suggesting that signaling through CheA(1) cannot initiate feedback receptor adaptation via CheB(1)-P.
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