ArticleMolecular and cellular biochemistry2001
Receptor-Ck regulates giardia encystation process.
Article in Molecular and cellular biochemistry, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 17 citations in OpenAlex.
- Functional characterization of AATF transcriptome in human leukemic cells.Molecular and cellular biochemistry · 2007Article
- Do genes from the cholesterol synthesis pathway exist and express in Giardia intestinalis?Parasitology research · 2006Article
- Role of cholesterol in parasitic infections.Lipids in health and disease · 2005Review
- Cholesterol-sensor initiates M. tuberculosis entry into human macrophages.Molecular and cellular biochemistry · 2004Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The study addressed to resolve the mechanism involved in cholesterol-dependent regulation of giardia encystation process, revealed that (a) the trophozoites have the ability to express genes coding for receptor-Ck and sterol element binding protein (SREBP); (b) inhibition of cholesterol dependent activation of receptor-Ck results in the upregulation of CWP-1 gene expression leading to encystation process. Based upon these findings, we propose that receptor-Ck dependent signalling is responsible for the regulation of giardia encystation process by cholesterol.
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