ArticleHeart (British Cardiac Society)2001
Patients' experiences of intervention trials on the treatment of myocardial infarction: is it time to adjust the informed consent procedure to the patient's capacity?
Article in Heart (British Cardiac Society), 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Views on consent approaches used in emergency and critical care research: a rapid, systematic review.Trials · 2026Pooled it
- Pooled it
- Pooled it
- The impact of processes of care on myocardial infarct size in patients with ST-segment elevation myocardial infarction: observations from the CRISP-AMI trial.Clinical cardiology · 2015Trial
- What a signature adds to the consent process.Surgical endoscopy · 2008Trial
- Advance Consent for participation in Acute Stroke Trials (ACTION): protocol for a feasibility study.Stroke and vascular neurology · 2025Article
- Ability of patients with acute ischemic stroke to recall given information on intravenous thrombolysis: Results of a prospective multicenter study.European stroke journal · 2023Observational
- Patients acceptance and comprehension to written and verbal consent (PAC-VC).BMC medical ethics · 2023Article
- Determinants of Patient and Surrogate Experiences With Acute Care Research Consent: A Key Informant Interview Study.Journal of the American Heart Association · 2019Article
- Review
- Variability in the Perception of Informed Consent for IV-tPA during Telestroke Consultation.Frontiers in neurology · 2012Article
- Article
- Patients' perception of the informed consent process for neurooncology clinical trials.Neuro-oncology · 2008Article
- Clinical research without consent in adults in the emergency setting: a review of patient and public views.BMC medical ethics · 2008Review
- 'No Time to be Lost!' Ethical considerations on consent for inclusion in emergency pharmacological research in severe traumatic brain injury in the European Union.Science and engineering ethics · 2007Article
- Emergency research without consent under Polish law.Science and engineering ethics · 2007Article
- Informed consent procedure for clinical trials in emergency settings: the Polish perspective.Science and engineering ethics · 2007Article
- Women's accounts of consenting to surgery: is consent a quality problem?Quality & safety in health care · 2004Article
- Is informed consent possible in acute myocardial infarction?Heart (British Cardiac Society) · 2004Article
- Patients' perceptions of informed consent in acute myocardial infarction research: a questionnaire based survey of the consent process in the DANAMI-2 trial.Heart (British Cardiac Society) · 2004Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate how patients included in trials on treatment in the early phase of acute myocardial infarction experience the consent procedure.
designA combined qualitative and quantitative interview concerning the patients' knowledge of the trial, their feelings about being asked to participate, and their attitudes towards the consent procedure.
settingTertiary referral centre. PATIENTS: 31 patients who had given written informed consent for their participation in randomised intervention trials of acute myocardial infarction.
resultsThe patients interviewed had only fragmentary knowledge about the trial they were involved in. Most considered that reading and signing a consent form was an unwanted or unnecessary procedure. Instead, they would have preferred to have been given concise verbal information about the study. Most were willing to allow a physician to decide for them in the event of their being too ill to be asked about their participation.
conclusionsPatients who are asked to participate in intervention trials in the early phase of acute myocardial infarction often appear to lack sufficient knowledge to reach an autonomous choice. There were problems and disadvantages associated with the process of obtaining written informed consent in this particular situation, especially regarding the need for the patient to sign a consent form during the acute phase of the disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.