ArticleAntimicrobial agents and chemotherapy2001
Expression of green fluorescent protein as a marker for effects of antileishmanial compounds in vitro.
Article in Antimicrobial agents and chemotherapy, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Reporter gene systems: A powerful tool forCurrent research in microbial sciences · 2022Article
- The effect of talc particles on phagocytes in co-culture with ovarian cancer cells.Environmental research · 2020Article
- Construction of Two mCherry Plasmids (pXG-mCherry) for TransgenicJournal of parasitology research · 2017Article
- In vitro screening test using Leishmania promastigotes stably expressing mCherry protein.Antimicrobial agents and chemotherapy · 2014Article
- Simple colorimetric trypanothione reductase-based assay for high-throughput screening of drugs against Leishmania intracellular amastigotes.Antimicrobial agents and chemotherapy · 2014Article
- An alternative in vitro drug screening test using Leishmania amazonensis transfected with red fluorescent protein.Diagnostic microbiology and infectious disease · 2013Article
- Multifunctional role of human SPLUNC1 in Pseudomonas aeruginosa infection.Infection and immunity · 2013Article
- Appraisal of a Leishmania major strain stably expressing mCherry fluorescent protein for both in vitro and in vivo studies of potential drugs and vaccine against cutaneous leishmaniasis.PLoS neglected tropical diseases · 2012Article
- Use of in vivo and in vitro systems to select Leishmania amazonensis expressing green fluorescent protein.The Korean journal of parasitology · 2011Article
- Luciferase-expressing Leishmania infantum allows the monitoring of amastigote population size, in vivo, ex vivo and in vitro.PLoS neglected tropical diseases · 2011Article
- The host range of gammaretroviruses and gammaretroviral vectors includes post-mitotic neural cells.PloS one · 2011Article
- Visceral leishmaniasis: experimental models for drug discovery.The Indian journal of medical research · 2011Review
- Delivering multiple gene products in the brain from a single adeno-associated virus vector.Gene therapy · 2009Article
- Leishmania (Viannia) panamensis: an in vitro assay using the expression of GFP for screening of antileishmanial drug.Experimental parasitology · 2009Article
- Real-time in vivo green fluorescent protein imaging of a murine leishmaniasis model as a new tool for Leishmania vaccine and drug discovery.Clinical and vaccine immunology : CVI · 2008Article
- Transgenic Leishmania and the immune response to infection.Parasite immunology · 2008Review
- Development of a fluorescence-based assay to screen antiviral drugs against Kaposi's sarcoma associated herpesvirus.Molecular cancer therapeutics · 2007Article
- Antileishmanial potential of a marine sponge, Haliclona exigua (Kirkpatrick) against experimental visceral leishmaniasis.Parasitology research · 2007Article
- Rab5b localization to early endosomes in the protozoan human pathogen Leishmania donovani.Molecular and cellular biochemistry · 2006Article
- Leishmania amastigotes as targets for drug screening.Kinetoplastid biology and disease · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Transgenic Leishmania infantum promastigotes, which constitutively express green fluorescent protein (GFP) in their cytoplasm, were used to monitor the effects of antileishmanial compounds in real time. The GFP-based assay provided a reliable measure of drug-induced inhibitory effects on protein expression, resulting in a dynamic picture of the responses of leishmanial promastigotes to the compounds tested.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.