ArticleAntimicrobial agents and chemotherapy2001
Newer macrolides as empiric treatment for acute Q fever infection.
Article in Antimicrobial agents and chemotherapy, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01095328 (Cost-effectiveness of a Screening Strategy for Q Fever Among Pregnant Women in Risk Areas), which is not on this map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cost-effectiveness of a Screening Strategy for Q Fever Among Pregnant Women in Risk Areas: a Clustered Randomized Controlled Trial
Who cites it
17 citing papers in PubMed, 63 citations in OpenAlex.
- Omadacycline in the treatment of severe Q fever pneumonia during an influenza epidemic: a case report with literature review.Frontiers in medicine · 2025Article
- Navigating Q fever: Current perspectives and challenges in outbreak preparedness.Open veterinary journal · 2024Review
- AcuteOpen forum infectious diseases · 2024Article
- Case Report of Acute Q Fever with Hepatitis Progressing to Chronic Q Fever with Endocarditis.Journal of community hospital internal medicine perspectives · 2023Article
- Article
- Etiologies of illness among patients meeting integrated management of adolescent and adult illness district clinician manual criteria for severe infections in northern Tanzania: implications for empiric antimicrobial therapy.The American journal of tropical medicine and hygiene · 2015Article
- Antimicrobial therapies for Q fever.Expert review of anti-infective therapy · 2013Review
- High Coxiella burnetii DNA load in serum during acute Q fever is associated with progression to a serologic profile indicative of chronic Q fever.Journal of clinical microbiology · 2013Article
- Molecular method for the characterization of Coxiella burnetii from clinical and environmental samples: variability of genotypes in Spain.BMC microbiology · 2012Article
- Unusual manifestations of acute Q fever: autoimmune hemolytic anemia and tubulointerstitial nephritis.Annals of clinical microbiology and antimicrobials · 2012Article
- Q Fever: current state of knowledge and perspectives of research of a neglected zoonosis.International journal of microbiology · 2011Article
- Real-time PCR with serum samples is indispensable for early diagnosis of acute Q fever.Clinical and vaccine immunology : CVI · 2010Article
- A case of acute q Fever with severe acute cholestatic hepatitis.Gut and liver · 2009Article
- Azithromycin for acute Q fever in pregnancy.Wiener klinische Wochenschrift · 2009Article
- Evaluation of Coxiella burnetii antibiotic susceptibilities by real-time PCR assay.Journal of clinical microbiology · 2003Article
- Q fever in adults: review of 66 clinical cases.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2003Review
- Use of macrolides for Q fever.Antimicrobial agents and chemotherapy · 2003Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The effectiveness of newer macrolides in acute Q fever for 113 patients was recorded. The mean times to defervescence were 2.9 days for doxycycline and 3.3, 3.9, 3.9, and 6.4 days for clarithromycin, roxithromycin, erythromycin, and beta-lactams, respectively (P < 0.01 for macrolides versus beta-lactams). We conclude that macrolides may be an adequate empirical antibiotic therapy for acute Q fever.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.