ArticleMedicina clinica2001
[Insulin resistance quantification by fasting insulin plasma values and HOMA index in a non-diabetic population].
Article in Medicina clinica, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04131582 (Effect of a Quadruple Therapy on Pancreatic Islet Function, Insulin Resistance and Cardiovascular Function in Patients With Mixed Prediabetes and Obesity), which is not on this map. Cited by 60 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of a Quadruple Therapy on Pancreatic Islet Function, Insulin Resistance and Cardiovascular Function in Patients With Mixed Prediabetes and Obesity: Randomized Clinical Trial
Who cites it
60 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Global prevalence of insulin resistance in the adult population: a systematic review and meta-analysis.Frontiers in endocrinology · 2025Pooled it
- Low vitamin D levels are linked with increased cardiovascular disease risk in young adults: a sub-study and secondary analyses from the ACTIBATE randomized controlled trial.Journal of endocrinological investigation · 2024Trial
- Influence of 12-Week Concurrent Training on Exosome Cargo and Its Relationship with Cardiometabolic Health Parameters in Men with Obesity.Nutrients · 2023Trial
- Trial
- Pioglitazone decreases ambulatory blood pressure in type 2 diabetics with difficult-to-control hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2007Trial
- Increased CX3CL1/CX3CR1 Axis Is Related to Atherosclerosis in Subjects with Familial Combined Hyperlipidaemia, Which Is Modulated by Insulin Resistance but Not by Sex.Biomedicines · 2025Article
- Article
- Validity of the MED4CHILD tool for assessing adherence to the Mediterranean diet in preschool children.European journal of pediatrics · 2025Article
- Discriminant Model for Insulin Resistance in Type 2 Diabetic Patients.Medicina (Kaunas, Lithuania) · 2023Observational
- Hypoxia-Inducible Factor 1-Alpha and Glucose Metabolism during Cardiac Remodeling Progression from Hypertrophy to Heart Failure.International journal of molecular sciences · 2023Article
- Identifying advanced MAFLD in a cohort of T2DM and clinical features.Frontiers in endocrinology · 2023Article
- Review
- Do Intestinal Unicellular Parasites Have a Role in the Inflammatory and Redox Status among the Severely Obese?Antioxidants (Basel, Switzerland) · 2022Article
- Interplay between Intestinal Bacterial Communities and Unicellular Parasites in a Morbidly Obese Population: A Neglected Trinomial.Nutrients · 2022Article
- Article
- Presence and significance of intestinal unicellular parasites in a morbidly obese population.International journal of obesity (2005) · 2022Article
- Cutoff point of TyG index for metabolic syndrome in Brazilian farmers.Archives of endocrinology and metabolism · 2021Article
- Correlates of olfactory impairment in middle-aged non-diabetic Caucasian subjects with stage I-II obesity.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2021Article
- Effect of a 12-Week Concurrent Training Intervention on Cardiometabolic Health in Obese Men: A Pilot Study.Frontiers in physiology · 2021Article
- Gender-Specific Behaviour in Obesity Stages I-II: Imbalance of Aminothiol Status and Adipomyokine Profile in Subjects with Different Insulin Resistance Severity.Oxidative medicine and cellular longevity · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOur goal was to determine the prevalence of insulin resistance (IR) by means of fasting insulin plasma values and the HOMA index,and to analyse the relation of these parameters with other components of the metabolic syndrome. SUBJECTS AND
methodWe studied 292 non-diabetic individuals, aged between 20 and 65 years, randomly selected from subjects attending an outpatient care center (Valencia-Spain-metropolitan area). 97 subjects who lacked clinical and biological criteria of IR were selected. In addition to calculating the HOMA index, anthropometric parameters, plasma lipids values, fasting glucose and insulin plasma levels were measured by standard methods in all subjects.
resultsIn the subgroup of 97 subjects without clinical and biological criteria of IR, we established a diagnosis of IR when the fasting plasma insulin value was >= 16.7 mU/l or the HOMA index was >= 3.8. Cut-off points of the percentil 90th of this subgroup were taken into account. In the whole group,the prevalence of IR (HOMA >= 3.8) was 31.8%, with a higher frequency in men compared to women.
conclusionsIn addition to fasting plasma insulin values and HOMA index, the best clinical and biochemical indicators of IR were fasting plasma glucose levels, BMI and triglycerides (TG) plasma values. Thus, the odds ratio for insulin resistance was 5.9 for a glycemia >= 110 mg/dl, 2.6% for BMI >= 25 kg/m(2) and 2.2 for triglycerides >= 150 mg/dl.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.