ArticleAmerican journal of human genetics2002
The map problem: a comparison of genetic and sequence-based physical maps.
Article in American journal of human genetics, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- Estimating recombination fraction via Pearson correlation.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- High-density linkage to physical mapping in a unique Tall × Dwarf coconut (Frontiers in plant science · 2024Article
- The chromosome-scale genome assembly of cluster bean provides molecular insight into edible gum (galactomannan) biosynthesis family genes.Scientific reports · 2023Article
- Replication of chromosomal loci involved in Parkinson's disease: A quantitative synthesis of GWAS.Toxicology reports · 2021Article
- From molecules to populations: appreciating and estimating recombination rate variation.Nature reviews. Genetics · 2020Review
- Genome-wide association mapping for adult resistance to powdery mildew in common wheat.Molecular biology reports · 2020Article
- Chromosome-scale scaffolding of the black raspberry (Horticulture research · 2018Article
- A genetic map of Xenopus tropicalis.Developmental biology · 2011Article
- Enhanced genetic maps from family-based disease studies: population-specific comparisons.BMC medical genetics · 2011Article
- Contrasting methods of quantifying fine structure of human recombination.Annual review of genomics and human genetics · 2010Review
- Large-scale integration of human genetic and physical maps.Genome research · 2004Article
- Age-related macular degeneration: a high-resolution genome scan for susceptibility loci in a population enriched for late-stage disease.American journal of human genetics · 2004Article
- Genetic maps of microsatellite and single-nucleotide polymorphism markers: are the distances accurate?Genetic epidemiology · 2003Article
- Growing evidence for diabetes susceptibility genes from genome scan data.Current diabetes reports · 2003Review
- Expressionview: visualization of quantitative trait loci and gene-expression data in Ensembl.Genome biology · 2003Article
- Map error reduction: using genetic and sequence-based physical maps to order closely linked markers.Human heredity · 2002Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The genetic order of autosomal genome-scan markers from Marshfield panels 9 and 10 were compared with their physical order, on the basis of the assembled nonredundant human genome sequence from the Human Genome Project-Santa Cruz (HGP-sc; October 2000 and April 2001 releases) and Celera (CEL; February 2001 release) databases. The genetic order of 96% of the markers on the Marshfield map for panel 10 is supported by a likelihood ratio of > or = 3 (odds ratio of 1,000:1). Inconsistencies with the genetic panel 10 map were found for 5% and 2% of the markers in the CEL and HGP-sc sequences, respectively. These inconsistencies consisted of both positional and chromosomal-assignment disagreements. For the majority of these inconsistent markers, the genetic order was supported by a likelihood ratio of > or = 3, and the physical order in the other assembly matched the genetic order. The majority of the inconsistencies between the physical- and genetic-map order point to errors in the physical-map order. A Web site is made available that displays inconsistencies for genetic markers from Marshfield panels 9 and 10 between their genetic-map positions and sequence-based physical-map positions, as well as inconsistencies between their sequence-based physical position. This Web site also contains genetic-map distances, physical-map positions from the Celera and Human Genome Project sequence, and likelihood-ratio support for the genetic maps.
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Registered trials
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