ArticlePlant physiology2001
Enhanced levels of the aroma and flavor compound S-linalool by metabolic engineering of the terpenoid pathway in tomato fruits.
Article in Plant physiology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.
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Who cites it
79 citing papers in PubMed, 307 citations in OpenAlex.
- Recent Advancements in Pentacyclic and Other Terpenoid Derivatives as Anti-inflammatory Agents.Mini reviews in medicinal chemistry · 2026Review
- Effect of rainy-day harvesting on the aroma profile of Wuyi rock tea based on GC-MS and chemical analysis.Food chemistry: X · 2025Article
- The SlGRAS9-SlMYC1 regulatory module controls glandular trichome formation and modulates resilience to pest in tomato.The Plant journal : for cell and molecular biology · 2025Article
- Expansion and functional divergence of terpene synthase genes in angiosperms: a driving force of terpene diversity.Horticulture research · 2025Article
- The synthesis of papaya fruit flavor-related linalool was regulated by CpTPS18 and CpNAC56.Plant reproduction · 2024Article
- Ketocarotenoid production in tomato triggers metabolic reprogramming and cellular adaptation: The quest for homeostasis.Plant biotechnology journal · 2024Article
- Improved antioxidant activities of spice require enrichment of distinct yet closely-related metabolic pathways.Heliyon · 2023Article
- Formation of 8-hydroxylinalool in tea plantFood chemistry. Molecular sciences · 2023Article
- Changes in the VOC of Fruits at Different Refrigeration Stages of 'Ruixue' and the Participation of CarboxylesteraseFoods (Basel, Switzerland) · 2023Article
- Analysis of Volatile and Nonvolatile Constituents in Gin by Direct-Infusion Ultrahigh-Resolution ESI/APPI FT-ICR Mass Spectrometry.Journal of agricultural and food chemistry · 2023Article
- Impact of odorants on perception of sweetness by honey bees.PloS one · 2023Article
- Characterization of key aroma compounds and regulation mechanism of aroma formation in local Binzi (Malus pumila × Malus asiatica) fruit.BMC plant biology · 2022Article
- Study on the differences in aroma components and formation mechanisms of "Nasmi" melon from different production areas.Food science & nutrition · 2022Article
- The metabolic changes that effect fruit quality during tomato fruit ripening.Molecular horticulture · 2022Review
- Combinatorial transient gene expression strategies to enhance terpenoid production in plants.Frontiers in plant science · 2022Article
- Article
- Metabolic Perturbation and Synthetic Biology Strategies for Plant Terpenoid Production-An Updated Overview.Plants (Basel, Switzerland) · 2021Review
- Synthesis of flavour-related linalool is regulated by PpbHLH1 and associated with changes in DNA methylation during peach fruit ripening.Plant biotechnology journal · 2021Article
- Comparative Metabolic Profiling of Grape Pulp during the Growth Process Reveals Systematic Influences under Root Restriction.Metabolites · 2021Article
- Identification of early and late flowering time candidate genes in endodormant and ecodormant almond flower buds.Tree physiology · 2021Article
19 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aromas of fruits, vegetables, and flowers are mixtures of volatile metabolites, often present in parts per billion levels or less. We show here that tomato (Lycopersicon esculentum Mill.) plants transgenic for a heterologous Clarkia breweri S-linalool synthase (LIS) gene, under the control of the tomato late-ripening-specific E8 promoter, synthesize and accumulate S-linalool and 8-hydroxylinalool in ripening fruits. Apart from the difference in volatiles, no other phenotypic alterations were noted, including the levels of other terpenoids such as gamma- and alpha-tocopherols, lycopene, beta-carotene, and lutein. Our studies indicate that it is possible to enhance the levels of monoterpenes in ripening fruits by metabolic engineering.
Indexed as
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11706204PMC129293W2130331264What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.