ArticleInfection and immunity2001
Chlamydia pneumoniae infects and multiplies in lymphocytes in vitro.
Article in Infection and immunity, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 58 citations in OpenAlex.
- Chlamydia pneumoniae infection of monocytes in vitro stimulates innate and adaptive immune responses relevant to those in Alzheimer's disease.Journal of neuroinflammation · 2014Article
- Chlamydia pneumoniae-induced foam cell formation requires MyD88-dependent and -independent signaling and is reciprocally modulated by liver X receptor activation.Journal of immunology (Baltimore, Md. : 1950) · 2008Article
- Novel Parachlamydia acanthamoebae quantification method based on coculture with amoebae.Applied and environmental microbiology · 2008Article
- Chlamydia pneumoniae growth inhibition in cells by the steroid receptor antagonist RU486 (mifepristone).Antimicrobial agents and chemotherapy · 2008Article
- Detection of Chlamydia in the peripheral blood cells of normal donors using in vitro culture, immunofluorescence microscopy and flow cytometry techniques.BMC infectious diseases · 2006Article
- Depletion of resident Chlamydia pneumoniae through leukoreduction by filtration of blood for transfusion.Journal of clinical microbiology · 2005Article
- Cytokine response of lymphocytes persistently infected with Chlamydia pneumoniae.Current microbiology · 2005Article
- Chlamydia pneumoniae resists antibiotics in lymphocytes.Antimicrobial agents and chemotherapy · 2003Article
- Involvement of nicotinic acetylcholine receptors in controlling Chlamydia pneumoniae growth in epithelial HEp-2 cells.Infection and immunity · 2003Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The obligate intracellular pathogen Chlamydia (Chlamydophila) pneumoniae is known to be associated with some chronic inflammatory diseases, such as atherosclerosis. Interaction between C. pneumoniae and immune cells is important in the development of such diseases. However, susceptibility of immune cells, particularly lymphocytes, to C. pneumoniae infection has not been reported, even though lymphocytes play a pivotal role in the development of the diseases caused by this bacterium. In this regard, we examined the susceptibility of lymphocytes to C. pneumoniae infection in vitro. The results demonstrated that human peripheral blood lymphocytes as well as mouse spleen lymphocytes could be infected with C. pneumoniae. Furthermore, purified T lymphocytes as well as established T-lymphocyte cell line cells showed an obvious susceptibility to C. pneumoniae infection, indicating that T cells could be one of the host cells for this bacterial infection. These findings reveal a new infection site for C. pneumoniae, i.e., lymphocytes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.