ArticleJournal of anatomy2001
Early nephron formation in the developing mouse kidney.
Article in Journal of anatomy, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 49 citations in OpenAlex.
- Connecting tubules develop from the tip of the ureteric bud in the human kidney.Histochemistry and cell biology · 2021Article
- Recapitulating kidney development: Progress and challenges.Seminars in cell & developmental biology · 2019Review
- The Journal of Anatomy: origin and evolution.Journal of anatomy · 2016Review
- Functional Human Podocytes Generated in Organoids from Amniotic Fluid Stem Cells.Journal of the American Society of Nephrology : JASN · 2016Article
- The glomerular parietal epithelial cell's responses are influenced by SM22 alpha levels.BMC nephrology · 2014Article
- Targeted therapy aimed at cancer stem cells: Wilms' tumor as an example.Pediatric nephrology (Berlin, Germany) · 2014Review
- Coordination of kidney organogenesis by Wnt signaling.Pediatric nephrology (Berlin, Germany) · 2014Review
- Chromatin-modifying agents reactivate embryonic renal stem/progenitor genes in human adult kidney epithelial cells but abrogate dedifferentiation and stemness.Cellular reprogramming · 2013Article
- In vivo maturation of functional renal organoids formed from embryonic cell suspensions.Journal of the American Society of Nephrology : JASN · 2012Article
- Wound healing in development.Birth defects research. Part C, Embryo today : reviews · 2012Review
- Uncharted waters: nephrogenesis and renal regeneration in fish and mammals.Pediatric nephrology (Berlin, Germany) · 2011Article
- Inhibiting angiotensin-converting enzyme promotes renal repair by limiting progenitor cell proliferation and restoring the glomerular architecture.The American journal of pathology · 2011Article
- Generation of easily accessible human kidney tubules on two-dimensional surfaces in vitro.Journal of cellular and molecular medicine · 2011Article
- Expression of stem cell markers in the human fetal kidney.PloS one · 2009Article
- The reaper-binding protein scythe modulates apoptosis and proliferation during mammalian development.Molecular and cellular biology · 2005Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This paper reports 3-dimensional confocal microscopy observations on how nephrogenic aggregates form from the NCAM- and Pax2-positive caps (4-5 cells deep) of condensed metanephric mesenchyme surrounding the duct tips of the mouse kidney. Aggregates of 6-8 cells are first seen at approximately E12.5-12.75 immediately proximal to this cap, closely abutting the duct surface. As the tip advances, NCAM expression is maintained in the cap but is otherwise restricted to aggregates whose cells rapidly epithelialise, forming tubules that invade the duct epithelium. Pax2 expression studies shows how the rind of nephrogenic blastemal cells forms: as duct tips extend towards the kidney surface, the associated Pax2+ cells form patches of cells on the kidney surface. These observations revise our knowledge of the timing and process of nephron initiation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.