ArticleProceedings of the National Academy of Sciences of the United States of America2001
Genetic evidence for adaptation-driven incipient speciation of Drosophila melanogaster along a microclimatic contrast in "Evolution Canyon," Israel.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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31 citing papers in PubMed, 124 citations in OpenAlex.
- Evolution of temperature preference behaviour amongiScience · 2025Article
- Pathogen infection alters the gene expression landscape of transposable elements in Drosophila melanogaster.G3 (Bethesda, Md.) · 2024Article
- Does evolution of echolocation calls and morphology in Molossus result from convergence or stasis?PloS one · 2020Article
- Genomic divergence and adaptive convergence inProceedings of the National Academy of Sciences of the United States of America · 2019Article
- Counties not countries: Variation in host specificity among populations of an aphid parasitoid.Evolutionary applications · 2019Article
- Aggression and courtship differences found in Drosophila melanogaster from two different microclimates at Evolution Canyon, Israel.Scientific reports · 2019Article
- Hawaiian picture-wingedEcology and evolution · 2019Article
- The behavior of adult Drosophila in the wild.PloS one · 2018Article
- Putative adaptive inter-slope divergence of transposon frequency in fruit flies (Drosophila melanogaster) at "Evolution Canyon", Mount Carmel, Israel.Biology direct · 2015Article
- Assessing the Risk of Invasion by Tephritid Fruit Flies: Intraspecific Divergence Matters.PloS one · 2015Article
- Divergence of Drosophila melanogaster repeatomes in response to a sharp microclimate contrast in Evolution Canyon, Israel.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
- Genome differentiation of Drosophila melanogaster from a microclimate contrast in Evolution Canyon, Israel.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Diversity in the origins of proteostasis networks--a driver for protein function in evolution.Nature reviews. Molecular cell biology · 2013Review
- Hsp90 is important for fecundity, longevity, and buffering of cryptic deleterious variation in wild fly populations.BMC evolutionary biology · 2012Article
- Article
- Evolution of hsp70 gene expression: a role for changes in AT-richness within promoters.PloS one · 2011Article
- Evolution under environmental stress at macro- and microscales.Genome biology and evolution · 2011Article
- Contrasting patterns of transposable element insertions in Drosophila heat-shock promoters.PloS one · 2009Article
- Review
- Duplicate gene evolution toward multiple fates at the Drosophila melanogaster HIP/HIP-Replacement locus.Journal of molecular evolution · 2009Article
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Substantial genetic differentiation, as great as among species, exists between populations of Drosophila melanogaster inhabiting opposite slopes of a small canyon. Previous work has shown that prezygotic sexual isolation and numerous differences in stress-related phenotypes have evolved between D. melanogaster populations in "Evolution Canyon," Israel, in which slopes 100-400 m apart differ dramatically in aridity, solar radiation, and associated vegetation. Because the canyon's width is well within flies' dispersal capabilities, we examined genetic changes associated with local adaptation and incipient speciation in the absence of geographical isolation. Here we report remarkable genetic differentiation of microsatellites and divergence in the regulatory region of hsp70Ba which encodes the major inducible heat shock protein of Drosophila, in the two populations. Additionally, an analysis of microsatellites suggests a limited exchange of migrants and lack of recent population bottlenecks. We hypothesize that adaptation to the contrasting microclimates overwhelms gene flow and is responsible for the genetic and phenotypic divergence between the populations.
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