ReviewRespiratory research2001
The neuropharmacology of upper airway motor control in the awake and asleep states: implications for obstructive sleep apnoea.
Review in Respiratory research, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 83 citations in OpenAlex.
- Leptin alleviates obesity hypoventilationbioRxiv : the preprint server for biology · 2026Article
- Cephalometric Measurements of Upper Airway at Upright and Supine Posture in Adult OSAS Patients.European journal of dentistry · 2026Article
- Cholinergic modulation of upper airway control: maturational changes and mechanisms at cellular and synaptic levels.Journal of neurophysiology · 2025Review
- Tackling obstructive sleep apnea with pharmacotherapeutics: expert guidance.Expert opinion on pharmacotherapy · 2024Review
- International Consensus Statement on Obstructive Sleep Apnea.International forum of allergy & rhinology · 2023Review
- Article
- Use of antipsychotics and the risk of acute respiratory failure among adults: A disease risk score-matched nested case-control study.British journal of clinical pharmacology · 2020Article
- Silencing of Hypoglossal Motoneurons Leads to Sleep Disordered Breathing in Lean Mice.Frontiers in neurology · 2018Article
- Ventilation and neurochemical changes during µ-opioid receptor activation or blockade of excitatory receptors in the hypoglossal motor nucleus of goats.Journal of applied physiology (Bethesda, Md. : 1985) · 2017Article
- Future of Sleep-Disordered Breathing Therapy Using a Mechanistic Approach.The Canadian journal of cardiology · 2015Review
- Raphe serotonergic neurons modulate genioglossus corticomotor activity in intermittent hypoxic rats.Respiratory research · 2014Article
- Short-term severe thyroid hormone deficiency does not influence sleep parameters.Sleep & breathing = Schlaf & Atmung · 2013Article
- Mechanical properties of the upper airway.Comprehensive Physiology · 2012Review
- Article
- Obstructive Sleep Apnoea: From pathogenesis to treatment: Current controversies and future directions.Respirology (Carlton, Vic.) · 2010Review
- Pathophysiology & genetics of obstructive sleep apnoea.The Indian journal of medical research · 2010Review
- Article
- Pharyngeal motor control and the pathogenesis of obstructive sleep apnea.Respiratory physiology & neurobiology · 2008Review
- Time- and dose-related effects of three 5-HT receptor ligands on the genioglossus activity in anesthetized and conscious rats.Sleep & breathing = Schlaf & Atmung · 2007Article
- Serotonergic modulation of inspiratory hypoglossal motoneurons in decerebrate dogs.Journal of neurophysiology · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obstructive sleep apnoea is a common and serious breathing problem that is caused by effects of sleep on pharyngeal muscle tone in individuals with narrow upper airways. There has been increasing focus on delineating the brain mechanisms that modulate pharyngeal muscle activity in the awake and asleep states in order to understand the pathogenesis of obstructive apnoeas and to develop novel neurochemical treatments. Although initial clinical studies have met with only limited success, it is proposed that more rational and realistic approaches may be devised for neurochemical modulation of pharyngeal muscle tone as the relevant neurotransmitters and receptors that are involved in sleep-dependent modulation are identified following basic experiments.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.