Evidence map›Paper›PMID 11686890›Full record

ReviewRespiratory research2001

Viruses, dendritic cells and the lung.

R S Peebles, B S Graham

Abstract readReview
In one paragraph

Review in Respiratory research, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Review
  2. The role of dendritic cells in COVID-19 infection.Emerging microbes & infections · 2023
    Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Human Immunodeficiency Virus Infection and Host Defense in the Lungs.Seminars in respiratory and critical care medicine · 2016
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Pulmonary DNA vaccination: concepts, possibilities and perspectives.Journal of controlled release : official journal of the Controlled Release Society · 2005
    Review
  13. Hantavirus infection of dendritic cells.Journal of virology · 2002
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

R S PeeblesDepartment of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
B S Graham

Funding

RESPIRATORY SYNCYTIAL VIRUS ON ALLERGIC AIRWAY DISEASER01AI045512 · NIAID · VANDERBILT UNIVERSITY · PI PEEBLES, RAY STOKES · 1999 to 2003
$1.2M
AIRWAY REACTIVITY INDUCED BY VIRUS (RSV) AND ALLERGYK08HL003730 · NHLBI · VANDERBILT UNIVERSITY · PI PEEBLES, RAY STOKES · 1997 to 2001
$221k
NHLBI NIH HHS K08-HL-03730NIAID NIH HHS R01 AI045512NIAID NIH HHS R01-AI-45512
6 · The paper itself

Abstract

The interaction between viruses and dendritic cells (DCs) is varied and complex. DCs are key elements in the development of a host response to pathogens such as viruses, but viruses have developed survival tactics to either evade or diminish the immune system that functions to kill and eliminate these micro-organisms. In the present review we summarize current concepts regarding the function of DCs in the immune system, our understanding of how viruses alter DC function to attenuate both the virus-specific and global immune response, and how we may be able to exploit DC function to prevent or treat viral infections.

Indexed as

AnimalsAntigen-Presenting CellsDendritic CellsHumansLungVirus Diseases

Identifiers

PMID11686890
PMCPMC59582

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.