ReviewRespiratory research2001
Pharmacology of airway afferent nerve activity.
Review in Respiratory research, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- EXPRESS: Products of oxidative stress and TRPA1 expression in the brainstem of rats after lung ischemia-reperfusion injury.Pulmonary circulation · 2019Article
- Airway Innervation and Plasticity in Asthma.Physiology (Bethesda, Md.) · 2019Review
- Breath of Life: The Respiratory Vagal Stimulation Model of Contemplative Activity.Frontiers in human neuroscience · 2018Article
- Interactions Between Dyspnea and the Brain Processing of Nociceptive Stimuli: Experimental Air Hunger Attenuates Laser-Evoked Brain Potentials in Humans.Frontiers in physiology · 2015Article
- Cardiac responses to 24 hrs hyperoxia in Bmp2 and Bmp4 heterozygous mice.Inhalation toxicology · 2013Article
- Toll-like receptor-2/6 and Toll-like receptor-9 agonists suppress viral replication but not airway hyperreactivity in guinea pigs.American journal of respiratory cell and molecular biology · 2013Article
- Activation of mouse bronchopulmonary C-fibres by serotonin and allergen-ovalbumin challenge.The Journal of physiology · 2012Article
- Perspective on the human cough reflex.Cough (London, England) · 2011Article
- KCa1.1 channel contributes to cell excitability in unmyelinated but not myelinated rat vagal afferents.American journal of physiology. Cell physiology · 2011Article
- Muscarinic receptor signaling in the pathophysiology of asthma and COPD.Respiratory research · 2006Review
- Nicotine and nonnicotine factors in cigarette addiction.Psychopharmacology · 2006Review
- Sensory transduction of pulmonary reactive oxygen species by capsaicin-sensitive vagal lung afferent fibres in rats.The Journal of physiology · 2005Article
- Subtypes of vagal afferent C-fibres in guinea-pig lungs.The Journal of physiology · 2004Article
- Activation of bronchopulmonary vagal afferent nerves with bradykinin, acid and vanilloid receptor agonists in wild-type and TRPV1-/- mice.The Journal of physiology · 2004Article
- Capsaicin-sensitive and -insensitive vagal bronchopulmonary C-fibres in the mouse.The Journal of physiology · 2003Article
- Neurology of allergic inflammation and rhinitis.Current allergy and asthma reports · 2002Review
- Improvement of lung ischemia-reperfusion injury by inhibition of microRNA-155 via reductions in neuroinflammation and oxidative stress of vagal afferent nerve.Pulmonary circulationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Afferent nerves in the airways serve to regulate breathing pattern, cough, and airway autonomic neural tone. Pharmacologic agents that influence afferent nerve activity can be subclassified into compounds that modulate activity by indirect means (e.g. bronchial smooth muscle spasmogens) and those that act directly on the nerves. Directly acting agents affect afferent nerve activity by interacting with various ion channels and receptors within the membrane of the afferent terminals. Whether by direct or indirect means, most compounds that enter the airspace will modify afferent nerve activity, and through this action alter airway physiology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.