ReviewRespiratory research2001
Acute oxygen sensing: diverse but convergent mechanisms in airway and arterial chemoreceptors.
Review in Respiratory research, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed.
- Are pulmonary neuroepithelial bodies sensors for acute airway hypoxia implicated in the central regulation of breathing?PloS one · 2026Article
- Mitochondrial iron-sulfur clusters: Structure, function, and an emerging role in vascular biology.Redox biology · 2021Review
- Pulmonary Sensory Receptors.Advances in anatomy, embryology, and cell biology · 2021Article
- Functional Exploration of the Pulmonary NEB ME.Advances in anatomy, embryology, and cell biology · 2021Article
- Mitochondria-controlled signaling mechanisms of brain protection in hypoxia.Frontiers in neuroscience · 2015Review
- NOX2 (gp91phox) is a predominant O2 sensor in a human airway chemoreceptor cell line: biochemical, molecular, and electrophysiological evidence.American journal of physiology. Lung cellular and molecular physiology · 2012Article
- Glial cells are involved in the exciting effects of doxapram on brainstem slices in vitro.Cellular and molecular neurobiology · 2010Article
- Modulation of chronic hypoxia-induced chemoreceptor hypersensitivity by NADPH oxidase subunits in rat carotid body.Journal of applied physiology (Bethesda, Md. : 1985) · 2010Article
- Pulmonary expression of voltage-gated calcium channels: special reference to sensory airway receptors.Histochemistry and cell biology · 2007Article
- A central role for ROS in the functional remodelling of L-type Ca2+ channels by hypoxia.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2005Review
- The oxygen sensing signal cascade under the influence of reactive oxygen species.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2005Review
- Down regulation of Kv3.4 channels by chronic hypoxia increases acute oxygen sensitivity in rabbit carotid body.The Journal of physiology · 2005Article
- Deficiency in type 1 insulin-like growth factor receptor in mice protects against oxygen-induced lung injury.Respiratory research · 2005Article
- Role of voltage-dependent calcium channels in stimulus-secretion coupling in rabbit carotid body chemoreceptor cells.The Journal of physiology · 2005Article
- Characterization of the Kv channels of mouse carotid body chemoreceptor cells and their role in oxygen sensing.The Journal of physiology · 2004Article
- Physiological and pathological responses to hypoxia.The American journal of pathology · 2004Review
- Vagal innervation of the air sacs in a songbird, Taenopygia guttata.Journal of anatomy · 2004Article
- Pivotal role of nucleotide P2X2 receptor subunit of the ATP-gated ion channel mediating ventilatory responses to hypoxia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2003Article
- Acute hypoxia occludes hTREK-1 modulation: re-evaluation of the potential role of tandem P domain K+ channels in central neuroprotection.The Journal of physiology · 2003Article
- Hypoxia inhibits human recombinant large conductance, Ca(2+)-activated K(+) (maxi-K) channels by a mechanism which is membrane delimited and Ca(2+) sensitive.The Journal of physiology · 2002Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Airway neuroepithelial bodies sense changes in inspired O2, whereas arterial O2 levels are monitored primarily by the carotid body. Both respond to hypoxia by initiating corrective cardiorespiratory reflexes, thereby optimising gas exchange in the face of a potentially deleterious O2 supply. One unifying theme underpinning chemotransduction in these tissues is K+ channel inhibition. However, the transduction components, from O2 sensor to K+ channel, display considerable tissue specificity yet result in analogous end points. Here we highlight how emerging data are contributing to a more complete understanding of O2 chemosensing at the molecular level.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.