ArticleJournal of clinical microbiology2001
Molecular epidemiology of rotaviruses in Nigeria: detection of unusual strains with G2P[6] and G8P[1] specificities.
Article in Journal of clinical microbiology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Article
- Molecular Characterization of Rotavirus From Under-Five Children Presenting With Diarrhea at a Tertiary Hospital in Northeast Nigeria.International journal of pediatrics · 2026Article
- Unveiling the Genomic Landscape of G2P[6] Rotavirus a Strains in Brazil: Evolutionary and Epidemiological Perspectives.Viruses · 2025Article
- Prevalence, genotype diversity, and zoonotic potential of bovine rotavirus A in Amhara National Regional State, Ethiopia: A multicenter cross-sectional study.Virus research · 2024Article
- Human rotavirus VP4 and VP7 genetic diversity and detection of GII norovirus in Ibadan as Nigeria introduces rotavirus vaccine.The Journal of international medical research · 2022Article
- Prevalence of rotavirus A infection and the detection of type G3P[11] strain in ruminants in Yobe state, Nigeria.Tropical animal health and production · 2020Article
- Species A Rotavirus (RVA) Isolated from Sewage in Nigeria, 2014: Close Genetic Relatedness of Partial G, P, and NSP4 Gene Sequences Encoding G1 with Cogent Genes of Other Asian and African Rotaviruses.Journal of pathogens · 2018Article
- Epidemiology of Rotavirus A in Nigeria: Molecular Diversity and Current Insights.Journal of pathogens · 2018Review
- Epidemiological Survey of Rotaviruses Responsible for Infantile Diarrhea by the Immunomolecular Technique in Cotonou (Benin, West Africa).International journal of microbiology · 2018Article
- FIRST MOLECULAR DETECTION AND VP7 (G) GENOTYPING OF GROUP A ROTAVIRUS BY SEMI-NESTED RT-PCR FROM SEWAGE IN NIGERIA.Revista do Instituto de Medicina Tropical de Sao Paulo · 2016Article
- Molecular Characterization of Human Rotavirus from Children with Diarrhoeal Disease in Sokoto State, Nigeria.Molecular biology international · 2016Article
- Comparative analysis of pentavalent rotavirus vaccine strains and G8 rotaviruses identified during vaccine trial in Africa.Scientific reports · 2015Article
- Assessment of the risks for human health of adenoviruses, hepatitis A virus, rotaviruses and enteroviruses in the Buffalo River and three source water dams in the Eastern Cape.Food and environmental virology · 2014Article
- Quantitative RT-PCR detection of hepatitis A virus, rotaviruses and enteroviruses in the Buffalo River and source water dams in the Eastern Cape Province of South Africa.International journal of environmental research and public health · 2012Article
- Detection of rotavirus from hospitalized diarrheic children in uttar pradesh, India.Indian journal of microbiology · 2012Article
- Prevalence and molecular genotyping of group a rotaviruses in Iranian children.Indian journal of virology : an official organ of Indian Virological Society · 2012Article
- Detection and genotyping of Korean porcine rotaviruses.Veterinary microbiology · 2010Article
- Emergence of unusual human rotavirus strains in Salento, Italy, during 2006-2007.BMC infectious diseases · 2009Article
- Genomic characterization of a novel group A lamb rotavirus isolated in Zaragoza, Spain.Virus genes · 2008Article
- Molecular characterization of novel G5 bovine rotavirus strains.Journal of clinical microbiology · 2006Article
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Abstract
During an epidemiological study on rotaviruses among diarrheic children in the northeastern and middle belt regions of Nigeria, the distribution of G and P types was investigated in 127 stool specimens. By PCR G typing, the G type of rotaviruses in 97 samples was identified. Interestingly, an unusual G8 type, as well as common G1, G2, and G3 types, was detected more frequently (31 of 112; 27.7%). Eleven samples contained multiple G types, and a G9 strain (Bulumkutu) was identified for one of the probable mixed infections. In PCR P typing, P[6] was detected most frequently, P[8] being the second most common type, while the P type of 73 samples could not be identified. One rotavirus strain with a G8 type specificity could be cultivated in cell culture, and the P type of this strain was found to be P[1], which is usually carried by bovine strains. When the combinations of G and P types were examined, the unusual strains G2P[6] and G8P[1] were often identified. Sequence analysis was performed for the VP7 gene of the G9 strain Bulumkutu and the VP4 and VP7 genes of G8P[1] strain HMG035. The VP7 sequence of the Nigerian serotype G9 was more closely related to that of a Brazilian strain than to those of other African strains. The VP7 and VP4 genes of G8P[1] strain HMG035 were found to be very similar to that of a Thai bovine strain A5, suggesting that bovine strains may have been transmitted directly to humans. These results highlight an unexpected diversity among rotavirus strains in Nigeria and emphasize the need for further serological and genetic surveys on more rotavirus strains in African countries, including Nigeria.
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