ArticleJournal of clinical microbiology2001
Helicobacter typhlonius sp. nov., a Novel Murine Urease-Negative Helicobacter Species.
Article in Journal of clinical microbiology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 64 citations in OpenAlex.
- Article
- Genome and pathogenicity analysis of Helicobacter mastomyrinus isolated from mice.Archives of microbiology · 2025Article
- Temporary consumption of western diet trains the immune system to reduce future gut inflammation.iScience · 2023Article
- Methylation-Independent Chemotaxis Systems Are the Norm for Gastric-ColonizingJournal of bacteriology · 2022Article
- Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells.Immunity · 2021Article
- ANCHOR: a 16S rRNA gene amplicon pipeline for microbial analysis of multiple environmental samples.Environmental microbiology · 2019Article
- Whole-Genome Sequencing and Bioinformatics as Pertinent Tools to SupportFrontiers in microbiology · 2019Article
- Biomarkers for classification and class prediction of stress in a murine model of chronic subordination stress.PloS one · 2018Article
- Minimal standards for describing new species belonging to the families Campylobacteraceae and Helicobacteraceae: Campylobacter, Arcobacter, Helicobacter and Wolinella spp.International journal of systematic and evolutionary microbiology · 2017Article
- Current Hypothesis for the Relationship between Dietary Rice Bran Intake, the Intestinal Microbiota and Colorectal Cancer Prevention.Nutrients · 2016Review
- The Complete Genome Sequence of the Murine Pathobiont Helicobacter typhlonius.Frontiers in microbiology · 2015Article
- Helicobacter apodemus sp. nov., a new Helicobacter species identified from the gastrointestinal tract of striped field mice in Korea.Journal of veterinary science · 2015Article
- Effects of medicated diet to eradicate Helicobacter spp. on growth, pathology, and infection status in Rag1-/- and nude mice.Journal of the American Association for Laboratory Animal Science : JAALAS · 2014Article
- Prevalence of helicobacter in laboratory mice in Thailand.Experimental animals · 2014Article
- Inflammatory bowel disease therapies and gut function in a colitis mouse model.BioMed research international · 2013Article
- The transcription factor T-bet regulates intestinal inflammation mediated by interleukin-7 receptor+ innate lymphoid cells.Immunity · 2012Article
- Helicobacter hepaticus infection in mice: models for understanding lower bowel inflammation and cancer.Mucosal immunology · 2011Review
- Effects of Helicobacter infection on research: the case for eradication of Helicobacter from rodent research colonies.Comparative medicine · 2009Review
- Helicobacter typhlonius and Helicobacter rodentium differentially affect the severity of colon inflammation and inflammation-associated neoplasia in IL10-deficient mice.Comparative medicine · 2008Article
- Helicobacter infection decreases reproductive performance of IL10-deficient mice.Comparative medicine · 2008Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
Over the past decade, several Helicobacter species have been isolated from rodents. With the advent of PCR for the diagnosis of infectious agents, it has become clear that several previously uncharacterized Helicobacter species also colonize rodents. In this report, we describe a novel urease-negative helicobacter, Helicobacter typhlonius sp. nov., which was isolated from colonies of laboratory mice independently by two laboratories. Infection of immunodeficient mice by this bacterium resulted in typhlocolitis similar to that observed with other helicobacter infections. H. typhlonius is genetically most closely related to H. hepaticus. Like H. hepaticus, it is a spiral bacterium with bipolar sheathed flagella. However, this novel species contains a large intervening sequence in its 16S rRNA gene and is biochemically distinct from H. hepaticus. Notably, H. typhlonius does not produce urease or H(2)S nor does it hydrolize indoxyl-acetate. Compared to other Helicobacter species that commonly colonize rodents, H. typhlonius was found to be less prevalent than H. hepaticus and H. rodentium but as prevalent as H. bilis. H. typhlonius joins a growing list of helicobacters that colonize mice and are capable of inducing enteric disease in various strains of immunodeficient mice.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.