ArticleClinical and experimental immunology2001
Screening of a HUVEC cDNA library with transplant-associated coronary artery disease sera identifies RPL7 as a candidate autoantigen associated with this disease.
Article in Clinical and experimental immunology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Mendelian randomization provides a multi-omics perspective on the regulation of genes involved in ribosome biogenesis in relation to cardiac structure and function.Clinical epigenetics · 2025Article
- Bioinformatics Analysis of Next Generation Sequencing Data Identifies Molecular Biomarkers Associated With Type 2 Diabetes Mellitus.Clinical medicine insights. Endocrinology and diabetes · 2023Article
- Article
- Association between serum anti‑ASXL2 antibody levels and acute ischemic stroke, acute myocardial infarction, diabetes mellitus, chronic kidney disease and digestive organ cancer, and their possible association with atherosclerosis and hypertension.International journal of molecular medicine · 2020Article
- Extracellular vesicles derived from injured vascular tissue promote the formation of tertiary lymphoid structures in vascular allografts.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2020Article
- New insights into immune mechanisms of antiperlecan/LG3 antibody production: Importance of T cells and innate B1 cells.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2019Article
- Elevation of Autoantibody in Patients with Ischemic Stroke.Neurologia medico-chirurgica · 2018Review
- Elevation of autoantibody level against PDCD11 in patients with transient ischemic attack.Oncotarget · 2018Article
- Identification of stroke-associated-antigens via screening of recombinant proteins from the human expression cDNA library (SEREX).Journal of translational medicine · 2015Article
- Pretransplant IgG reactivity to apoptotic cells correlates with late kidney allograft loss.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2014Article
- Polyreactive antibodies developing amidst humoral rejection of human kidney grafts bind apoptotic cells and activate complement.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2013Article
- Antibodies in transplantation: the effects of HLA and non-HLA antibody binding and mechanisms of injury.Methods in molecular biology (Clifton, N.J.) · 2013Article
- Expansion of polyreactive B cells cross-reactive to HLA and self in the blood of a patient with kidney graft rejection.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2012Article
- Characterization of immune responses to cardiac self-antigens myosin and vimentin in human cardiac allograft recipients with antibody-mediated rejection and cardiac allograft vasculopathy.The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation · 2010Article
- Chronic humoral rejection of human kidney allografts associates with broad autoantibody responses.Transplantation · 2010Article
- Autoantibodies to vimentin cause accelerated rejection of cardiac allografts.The American journal of pathology · 2007Article
- Human lysyl-tRNA synthetase is secreted to trigger proinflammatory response.Proceedings of the National Academy of Sciences of the United States of America · 2005Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A HUVEC cDNA library was screened with sera from two patients who had developed transplant-associated coronary artery disease (TxCAD) following cardiac transplantation. A total of six positive clones were isolated from a primary screen of 40 000 genes. Subsequent DNA sequence analysis identified these to be lysyl tRNA synthetase, ribosomal protein L7, ribosomal protein L9, beta transducin and TANK. Another gene whose product could not be identified showed homology to a human cDNA clone (DKFZp566M063) derived from fetal kidney. Full-length constructs of selected genes were expressed as his-tag recombinant fusion proteins and used to screen a wider patient base by ELISA to determine prevalence and association with TxCAD. Of these ribosomal protein L7 showed the highest prevalence (55.6%) with TxCAD sera compared to 10% non-CAD.
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