ArticleAJNR. American journal of neuroradiology2001
Intracranial and spinal MR imaging findings associated with Krabbe's disease: case report.
Article in AJNR. American journal of neuroradiology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The trial behind it
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Who cites it
10 citing papers in PubMed, 32 citations in OpenAlex.
- NovelFrontiers in neurology · 2020Article
- Report of a Case that Expands the Phenotype of Infantile Krabbe Disease.The American journal of case reports · 2019Article
- Biochemical, cell biological, pathological, and therapeutic aspects of Krabbe's disease.Journal of neuroscience research · 2016Review
- Thickening of the cauda equina roots: a common finding in Krabbe disease.European radiology · 2016Article
- Enlargement of the brachial plexus on magnetic resonance imaging: a novel finding in adult-onset Krabbe disease.BJR case reports · 2016Article
- Diffusion tensor imaging detects axonal injury and demyelination in the spinal cord and cranial nerves of a murine model of globoid cell leukodystrophy.NMR in biomedicine · 2009Article
- Krabbe disease: unusual MRI findings.Pediatric radiology · 2006Article
- Spinal cord and cauda equina MRI findings in metachromatic leukodystrophy: case report.Neuroradiology · 2005Article
- Tools for diagnosis of leukodystrophies and other disorders presenting with white matter disease.Current neurology and neuroscience reports · 2005Review
- Prevalence, Clinic-Etiological Spectrum and Outcome of Pediatric Metabolic Epilepsy - A Single Centre Experience.Annals of Indian Academy of NeurologyArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Krabbe's disease is an autosomal recessive leukodystrophy with well-documented intracranial findings on both CT scans and MR images. We herein present what is thought to be the second case of Krabbe's disease with spinal involvement shown on MR images as abnormal contrast enhancement of the lumbosacral nerve roots. The typical intracranial findings of T2 hyperintensity without contrast enhancement were present within the periventricular white matter, but there was no area of abnormal signal intensity or enhancement within the substance of the spinal cord. We briefly review the pathophysiology, clinical presentation, and imaging findings of Krabbe's disease. Spinal abnormalities may precede the onset of brain abnormalities, and MR imaging may be a useful diagnostic tool in cases of Krabbe's disease and other leukodystrophies.
Indexed as
Identifiers
11673180PMC7974452W2158173954What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.