ReviewRespiratory research2000
Early glandular neoplasia of the lung.
Review in Respiratory research, 2000. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.
- International association for the study of lung cancer/american thoracic society/european respiratory society international multidisciplinary classification of lung adenocarcinoma.Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer · 2011Pooled it
- Development of a CT-based comprehensive model with deep learning for differentiating pathological types of pulmonary ground-glass nodules.Frontiers in medicine · 2026Article
- Early Diagnosis and Screening for Lung Cancer.Cold Spring Harbor perspectives in medicine · 2021Review
- Pathological and Prognostic Indications of the mdig Gene in Human Lung Cancer.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology · 2021Article
- Review
- Tumor evolution in epidermal growth factor receptor mutated non-small cell lung cancer.Journal of thoracic disease · 2020Review
- Rationale for Lung Adenocarcinoma Prevention and Drug Development Based on Molecular Biology During Carcinogenesis.OncoTargets and therapy · 2020Review
- Inhalation of gas metal arc-stainless steel welding fume promotes lung tumorigenesis in A/J mice.Archives of toxicology · 2017Article
- Targeted sequencing reveals clonal genetic changes in the progression of early lung neoplasms and paired circulating DNA.Nature communications · 2015Article
- Combinatorial Action of MicroRNAs let-7 and miR-34 Effectively Synergizes with Erlotinib to Suppress Non-small Cell Lung Cancer Cell Proliferation.Cell cycle (Georgetown, Tex.) · 2015Article
- C4.4A as a biomarker in pulmonary adenocarcinoma and squamous cell carcinoma.World journal of clinical oncology · 2014Review
- Pulmonary adenocarcinoma: a renewed entity in 2011.Respirology (Carlton, Vic.) · 2012Review
- DNA methylation changes in atypical adenomatous hyperplasia, adenocarcinoma in situ, and lung adenocarcinoma.PloS one · 2011Article
- Epidermal growth factor receptor gene amplification in atypical adenomatous hyperplasia of the lung.American journal of translational research · 2010Article
- Lung cancer cytology: potential pitfalls and mimics - a review.International journal of clinical and experimental pathology · 2010Review
- Chemoprevention of lung cancer.Proceedings of the American Thoracic Society · 2009Review
- Lung cancer.The New England journal of medicine · 2008Review
- Pulmonary inflammation and tumor induction in lung tumor susceptible A/J and resistant C57BL/6J mice exposed to welding fume.Particle and fibre toxicology · 2008Article
- Epidermal growth factor receptor abnormalities in the pathogenesis and progression of lung adenocarcinomas.Cancer prevention research (Philadelphia, Pa.) · 2008Article
- Epigenetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung.Carcinogenesis · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although bronchogenic carcinomas progress through a very well defined sequence of metaplasia, dysplasia and carcinoma in situ, very little is known about the early progression of glandular neoplasms of the lung. In particular, the early precursor lesion from which fully malignant adenocarcinomas arise has effectively eluded recognition, at least until recently. Several lines of evidence now implicate atypical adenomatous hyperplasia (AAH) as an initial morphologic stage in multistep lung tumorigenesis. Despite its small size, AAH can be appreciated at the light microscopic level and characterized at the molecular genetic level. Indeed, the genetic characterization of AAH promises to further our understanding of lung cancer development and might facilitate the design of novel strategies for early detection of lung cancer.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.