ArticleBiophysical journal2001
Intramural multisite recording of transmembrane potential in the heart.
Article in Biophysical journal, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Optical mapping of contracting hearts.The Journal of physiology · 2023Review
- In vivo ratiometric optical mapping enables high-resolution cardiac electrophysiology in pig models.Cardiovascular research · 2019Article
- Marker-Free Tracking for Motion Artifact Compensation and Deformation Measurements in Optical Mapping Videos of Contracting Hearts.Frontiers in physiology · 2018Article
- Optical Mapping of Membrane Potential and Epicardial Deformation in Beating Hearts.Biophysical journal · 2016Article
- Toward microendoscopy-inspired cardiac optogenetics in vivo: technical overview and perspective.Journal of biomedical optics · 2014Review
- A century of optocardiography.IEEE reviews in biomedical engineering · 2014Review
- Cardiac optogenetics.American journal of physiology. Heart and circulatory physiology · 2013Review
- Cardiac electrophysiological imaging systems scalable for high-throughput drug testing.Pflugers Archiv : European journal of physiology · 2012Article
- Optical imaging of voltage and calcium in cardiac cells & tissues.Circulation research · 2012Review
- A new optrode design for intramural optical recordings.IEEE transactions on bio-medical engineering · 2011Article
- Mapping of cardiac electrical activation with electromechanical wave imaging: an in silico-in vivo reciprocity study.Heart rhythm · 2011Article
- Construction and validation of anisotropic and orthotropic ventricular geometries for quantitative predictive cardiac electrophysiology.Interface focus · 2011Article
- Evaluating intramural virtual electrodes in the myocardial wedge preparation: simulations of experimental conditions.Biophysical journal · 2008Article
- Optical measurements of intramural action potentials in isolated porcine hearts using optrodes.Heart rhythm · 2007Article
- A fiber-based ratiometric optical cardiac mapping channel using a diffraction grating and split detector.Biophysical journal · 2007Article
- A MULTICHANNEL FIBER-OPTIC MAPPING SYSTEM FOR INTRAMURAL RECORDING OF CARDIAC ACTION POTENTIALS.IFMBE proceedings · 2005Article
- High resolution magnetic images of planar wave fronts reveal bidomain properties of cardiac tissue.Biophysical journal · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heart surface optical mapping of transmembrane potentials has been widely used in studies of normal and pathological heart rhythms and defibrillation. In these studies, three-dimensional spatio-temporal events can only be inferred from two-dimensional surface potential maps. We present a novel optical system that enables high fidelity transmural recording of transmembrane potentials. A probe constructed from optical fibers is used to deliver excitation light and collect fluorescence from seven positions, each 1 mm apart, through the left ventricle wall of the rabbit heart. Excitation is provided by the 488-nm line of a water-cooled argon-ion laser. The fluorescence of the voltage-sensitive dye di-4-ANEPPS from each tissue site is split at 600 nm and imaged onto separate photodiodes for later signal ratioing. The optics and electronics are easily expandable to accommodate multiple optical probes. The system is used to record the first simultaneous measurements of transmembrane potential at a number of sites through the intact heart wall.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.