ArticleBiophysical journal2001
A two-state piezoelectric model for outer hair cell motility.
Article in Biophysical journal, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- Electromotility can be disassociated from gating charge movement in outer hair cells of conditional alpha2 spectrin knockout mice.The Journal of biological chemistry · 2026Article
- Structural Mechanism of Prestin-Membrane Mechanotransduction.bioRxiv : the preprint server for biology · 2025Article
- Rate-dependent cochlear outer hair cell force generation: Models and parameter estimation.Biophysical journal · 2024Article
- Elevator-like movements of prestin mediate outer hair cell electromotility.Nature communications · 2023Article
- Article
- State dependent effects on the frequency response of prestin's real and imaginary components of nonlinear capacitance.Scientific reports · 2021Article
- Kinetic Membrane Model of Outer Hair Cells.Biophysical journal · 2021Article
- The cochlear outer hair cell speed paradox.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Prestin kinetics and corresponding frequency dependence augment during early development of the outer hair cell within the mouse organ of Corti.Scientific reports · 2019Article
- Two-Dimensional Brain Microtubule Structures Behave as Memristive Devices.Scientific reports · 2019Article
- Energy Output from a Single Outer Hair Cell.Biophysical journal · 2016Article
- Prestin is an anion transporter dispensable for mechanical feedback amplification in Drosophila hearing.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2015Article
- Chloride and salicylate influence prestin-dependent specific membrane capacitance: support for the area motor model.The Journal of biological chemistry · 2014Article
- Molecular architecture and the structural basis for anion interaction in prestin and SLC26 transporters.Nature communications · 2014Article
- Progress in cochlear physiology after Békésy.Hearing research · 2012Review
- The capacitance and electromechanical coupling of lipid membranes close to transitions: the effect of electrostriction.Biophysical journal · 2012Article
- Article
- A synthetic prestin reveals protein domains and molecular operation of outer hair cell piezoelectricity.The EMBO journal · 2011Article
- Coupling active hair bundle mechanics, fast adaptation, and somatic motility in a cochlear model.Biophysical journal · 2011Article
- Membrane thickness sensitivity of prestin orthologs: the evolution of a piezoelectric protein.Biophysical journal · 2011Article
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1 author.
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Abstract
Recent studies have revealed that voltage-dependent length changes of the outer hair cell are based on charge transfer across the membrane. Such a motility can be explained by an "area motor" model, which assumes two states in the motor and that conformational transitions involve transfer of motor charge across the membrane and mechanical displacements of the membrane. Here it is shown that the area motor is piezoelectric and that the hair cell that incorporates such a motor in its lateral membrane is also piezoelectric. Distinctive features of the outer hair cell are its exceptionally large piezoelectric coefficient, which exceeds the best known piezoelectric material by four orders of magnitude, and its prominent nonlinearity due to the discreteness of motor states.
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