ArticleCell stress & chaperones2001
Activation of human monocyte cell line U937 via cell surface calreticulin.
Article in Cell stress & chaperones, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 24 citations in OpenAlex.
- Potential role of an antimicrobial peptide, KLK in inhibiting lipopolysaccharide-induced macrophage inflammation.PloS one · 2017Article
- Article
- Dendritic cell activation and maturation induced by recombinant calreticulin fragment 39-272.International journal of clinical and experimental medicine · 2015Article
- Soluble calreticulin induces tumor necrosis factor-α (TNF-α) and interleukin (IL)-6 production by macrophages through mitogen-activated protein kinase (MAPK) and NFκB signaling pathways.International journal of molecular sciences · 2014Article
- Oxidative stress-induced calreticulin expression and translocation: new insights into the destruction of melanocytes.The Journal of investigative dermatology · 2014Article
- Self-oligomerization is essential for enhanced immunological activities of soluble recombinant calreticulin.PloS one · 2013Article
- Cationic amphipathic peptides accumulate sialylated proteins and lipids in the plasma membrane of eukaryotic host cells.Biochimica et biophysica acta · 2011Article
- A role for calreticulin in the pathogenesis of rheumatoid arthritis.Annals of the New York Academy of Sciences · 2010Review
- Prevention of death in bacterium-infected mice by a synthetic antimicrobial peptide, L5, through activation of host immunity.Antimicrobial agents and chemotherapy · 2009Article
- Low density lipoprotein receptor-related protein is a calreticulin coreceptor that signals focal adhesion disassembly.The Journal of cell biology · 2003Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
U937 cells were found to be activated by an antibacterial peptide, KLKLLLLLKLK-NH2 (L5), to generate superoxide anion (O2-)-like peripheral neutrophils. However, the state of cell surface calreticulin, a possible receptor for L5, was suggested to differ between neutrophils and U937 cells. Unlike the former, the latter ones were activated by anti-C-domain peptide antibody of calreticulin even in the absence of L5 and generated O2- in a GTP-binding protein (G-protein)-dependent manner.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.