Evidence map›Paper›PMID 11598094›Full record

ArticleInfection and immunity2001

Resistance of T-cell receptor delta-chain-deficient mice to experimental Candida albicans vaginitis.

F L Wormley, C Steele, K Wozniak, K Fujihashi, J R McGhee, P L Fidel

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Applying the Host-Microbe Damage Response Framework toJournal of fungi (Basel, Switzerland) · 2020
    Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. T-cell Subsets and Antifungal Host Defenses.Current fungal infection reports · 2010
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

F L WormleyDepartment of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA.
C Steele
K Wozniak
K Fujihashi
J R McGhee
P L Fidel
Louisiana State University Health Sciences Center New Orleans · USUniversity of Alabama at Birmingham · US

Funding

MUCOSAL CELL MEDIATED IMMUNITY IN VAGINAL CANDIDIASISR01AI032556 · NIAID · LSU HEALTH SCIENCES CENTER · PI FIDEL, PAUL L · 2000 to 2006
$1.3M
MUCOSAL CELL MEDIATED IMMUNITY IN VAGINAL CANDIDIASISR29AI032556 · NIAID · WAYNE STATE UNIVERSITY · PI FIDEL, PAUL L · 1995 to 1999
–
NIAID NIH HHS AI 32556NIAID NIH HHS R01 AI032556NIAID NIH HHS R29 AI032556
6 · The paper itself

Abstract

Conditions consistent with tolerance or immunoregulation have been observed in experimental Candida albicans vaginal infections. The present study investigated the role of gamma/delta T cells in experimental vaginal candidiasis. Results showed that T-cell receptor delta-chain-knockout mice had significantly less vaginal fungal burden when compared to wild-type mice, suggesting an immunoregulatory role for gamma/delta T cells in Candida vaginitis.

Indexed as

AnimalsCandidiasisDisease Models, AnimalFemaleHypersensitivity, DelayedMiceMice, Inbred C57BLMice, KnockoutNitrogen OxidesReceptors, Antigen, T-Cell, gamma-deltaTh1 CellsTh2 CellsT-LymphocytesVaginitisNitrogen OxidesReceptors, Antigen, T-Cell, gamma-delta

Identifiers

PMID11598094
PMCPMC100112
OpenAlexW2112191495

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.