Evidence map›Paper›PMID 11594457›Full record

ReviewImmunologic research2001

Regulation of tumor growth by IFN-gamma in cancer immunotherapy.

G L Beatty, Y Paterson

Abstract readReview
PubMed Publisher
In one paragraph

Review in Immunologic research, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 94 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Concentration-dependent Early Antivascular and Antitumor Effects of Itraconazole in Non-Small Cell Lung Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2020
    Article
  12. Review
  13. Article
  14. Article
  15. Comprehensive network map of interferon gamma signaling.Journal of cell communication and signaling · 2018
    Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

G L BeattyDepartment of Microbiology, University of Pennsylvannia, Philadelphia, USA.
Y Paterson
University of Pennsylvania · US

Funding

IMMUNOBIOLOGY OF NORMAL AND NEOPLASTIC LYMPHOCYTEST32CA009140 · NCI · UNIVERSITY OF PENNSYLVANIA · PI Malay Haldar, WARREN S PEAR · 1985 to 2026
$16.1M
CANCER IMMUNOTHERAPY WITH A LIVE RECOMBINANT VACCINER01CA069632 · NCI · UNIVERSITY OF PENNSYLVANIA · PI PATERSON, YVONNE J · 1996 to 2011
$3.1M
NCI NIH HHS CA69632NCI NIH HHS T32CA09140
6 · The paper itself

Abstract

Tumor immunity involves a concerted interplay between cytokines and effector cells. Extensive efforts have focused on understanding the roles of cytokines and their interactions with effector cells for the production of effective tumor immunity. One cytokine that is well recognized to play a central role in coordinating tumor immune responses is IFN-gamma. IFN-gamma exerts its biological effects through interaction with an IFN-gamma receptor that is ubiquitously expressed on nearly all cells. In this review, we discuss the positive and negative effects of IFN-gamma signaling in the tumor cell on tumor growth.

Indexed as

ImmunotherapyInterferon-gammaInterferon gamma ReceptorLymphocytes, Tumor-InfiltratingNeoplasmsNeovascularization, PathologicReceptors, InterferonSignal TransductionT-LymphocytesInterferon-gammaInterferon gamma ReceptorReceptors, Interferon

Identifiers

PMID11594457
OpenAlexW2013525973

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.