Trial reportThe British journal of general practice : the journal of the Royal College of General Practitioners2001
Randomised controlled trial of tailored strategies to implement guidelines for the management of patients with depression in general practice.
Trial report in The British journal of general practice : the journal of the Royal College of General Practitioners, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01047124 (Randomised Control Trial of the Clinical and Cost Effectiveness of a Specialist Expert Mood Disorder Team for Refractory Unipolar Depressive Disorder), which is not on this map. Cited by 35 papers, 10 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Randomised Control Trial of the Clinical and Cost Effectiveness of a Specialist Expert Mood Disorder Team for Refractory Unipolar Depressive Disorder
Who cites it
35 citing papers in PubMed, 10 syntheses or guidelines pooled it, 105 citations in OpenAlex.
- Tailored interventions to address determinants of practice.The Cochrane database of systematic reviews · 2026Pooled it
- Adherence to evidence-based treatment guidelines for depression: a systematic review.BMC psychiatry · 2025Pooled it
- Elusive search for effective provider interventions: a systematic review of provider interventions to increase adherence to evidence-based treatment for depression.Implementation science : IS · 2018Pooled it
- Tools developed and disseminated by guideline producers to promote the uptake of their guidelines.The Cochrane database of systematic reviews · 2016Pooled it
- Consultation liaison in primary care for people with mental disorders.The Cochrane database of systematic reviews · 2015Pooled it
- Tailored interventions to address determinants of practice.The Cochrane database of systematic reviews · 2015Pooled it
- Interventions for enhancing medication adherence.The Cochrane database of systematic reviews · 2014Pooled it
- Does GP training in depression care affect patient outcome? - A systematic review and meta-analysis.BMC health services research · 2012Pooled it
- Tailored interventions to overcome identified barriers to change: effects on professional practice and health care outcomes.The Cochrane database of systematic reviews · 2010Pooled it
- Educational outreach visits: effects on professional practice and health care outcomes.The Cochrane database of systematic reviews · 2007Pooled it
- Effectiveness of a tailored implementation strategy to improve adherence to a guideline on mental health problems in occupational health care.BMC health services research · 2019Trial
- A tailored intervention to implement guideline recommendations for elderly patients with depression in primary care: a pragmatic cluster randomised trial.Implementation science : IS · 2016Trial
- Effectiveness of a tailored implementation programme to improve recognition, diagnosis and treatment of anxiety and depression in general practice: a cluster randomised controlled trial.Implementation science : IS · 2015Trial
- Effect of educational outreach on general practice prescribing of antibiotics and antidepressants: a two-year randomised controlled trial.Scandinavian journal of primary health care · 2009Trial
- Improving prescribing of antihypertensive and cholesterol-lowering drugs: a method for identifying and addressing barriers to change.BMC health services research · 2004Trial
- Cluster randomised controlled trial of an educational outreach visit to improve influenza and pneumococcal immunisation rates in primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2002Trial
- Cluster randomised controlled trial of tailored interventions to improve the management of urinary tract infections in women and sore throat.BMJ (Clinical research ed.) · 2002Trial
- Integrating insights from implementation science and behavioral economics to strengthen suicide screening strategies for pediatric populations.Current opinion in psychology · 2024Review
- Conventional and living guideline for schizophrenia: barriers and facilitating factors in guideline implementation.European archives of psychiatry and clinical neuroscience · 2024Article
- Training approaches for the dissemination of clinical guidelines for NSSI: a quasi-experimental trial.Child and adolescent psychiatry and mental health · 2024Article
Corrections and comments
- Commented on by
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVarious methods are available for implementing change in the clinical behaviour of general practitioners (GPs). Although passive dissemination of information is generally ineffective, other methods can be variably effective. Few studies have investigated the impact of tailored methods.
aimTo determine whether methods tailored to overcome obstacles to change using psychological theories are more effective than dissemination alone in the implementation of guidelines for depression among GPs. DESIGN OF STUDY: Randomised controlled trial.
settingSixty general practices in England; 30 GPs in the control group, 34 in the intervention group.
methodPractitioners identified patients presenting with depression before and after the implementation of guidelines (control group n = 192 in the first data collection, n = 181 in the second; intervention group n = 210 in the first data collection and n = 197 in the second). The main outcome measures were: record of adherence to guideline recommendations in clinical records; proportion of patients with Beck Depression Inventory (BDI) score less than 11 at 16 weeks after diagnosis.
resultsIn comparison with the control group, in the group of GPs receiving tailored implementation, there were increases in the proportions of patients assessed for suicide risk. In the intervention group, the proportion of patients with BDI scores of less than 11 at 16 weeks increased.
conclusionObstacles to implementation can be identified and strategies tailored to address them. The findings indicate a new approach for research to understand and develop methods of implementation.
Indexed as
Identifiers
11593835PMC1314102W2145519394What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.