ArticleProceedings of the National Academy of Sciences of the United States of America2001
Plant defense in the absence of jasmonic acid: the role of cyclopentenones.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 222 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
222 citing papers in PubMed, 1 synthesis or guideline pooled it, 711 citations in OpenAlex.
- Reciprocal responses in the interaction between Arabidopsis and the cell-content-feeding chelicerate herbivore spider mite.Plant physiology · 2014Pooled it
- Molecular Mechanisms and Network Integration of Oxylipin Signaling in Plant Abiotic Stress Tolerance.International journal of molecular sciences · 2026Review
- Arabidopsides as Signatory Biomarkers of theInternational journal of molecular sciences · 2026Review
- Molecular changes in agroinfiltrated leaves of Nicotiana benthamiana expressing suppressor of silencing P19 and coronavirus-like particles.Plant biotechnology journal · 2026Article
- A new 13-lipoxygenase from Taxus media callus is functionally linked to paclitaxel biosynthesis.Scientific reports · 2025Article
- Pulsed Electric Fields Reshape the Malting Barley Metabolome: Insights from UHPLC-HRMS/MS.Molecules (Basel, Switzerland) · 2025Article
- Downstream metabolites of (+)-cis-12-oxo-phytodienoic acid function as noncanonical bioactive jasmonates in Arabidopsis thaliana.Nature communications · 2025Article
- Transcriptomics and trans-organellar complementation reveal limited signaling of 12-cis-oxo-phytodienoic acid during early wound response in Arabidopsis.Nature communications · 2025Article
- OsJAZ10 Modulates Metabolite Profiles in Rice Seedlings in Response to Alkaline Stress.Rice (New York, N.Y.) · 2025Article
- A single-cell transcriptome atlas reveals the trajectory of early cell fate transition during callus induction in Arabidopsis.Plant communications · 2024Article
- Analysis of homodimer formation in 12-oxophytodienoate reductase 3 in solutio and crystallo challenges the physiological role of the dimer.Scientific reports · 2024Article
- Molecular responses of agroinfiltrated Nicotiana benthamiana leaves expressing suppressor of silencing P19 and influenza virus-like particles.Plant biotechnology journal · 2024Review
- Deciphering Aphanomyces euteiches-pea-biocontrol bacterium interactions through untargeted metabolomics.Scientific reports · 2024Article
- Article
- Integrated transcriptomic and pathway analyses of sorghum plants revealed the molecular mechanisms of host defense against aphids.Frontiers in plant science · 2024Article
- Integrative transcriptomics reveals association of abscisic acid and lignin pathways with cassava whitefly resistance.BMC plant biology · 2023Article
- RVE2, a new regulatory factor in jasmonic acid pathway, orchestrates resistance to Verticillium wilt.Plant biotechnology journal · 2023Article
- PSI Photoinhibition and Changing COAntioxidants (Basel, Switzerland) · 2023Article
- Article
- Loss of Chloroplast GNAT Acetyltransferases Results in Distinct Metabolic Phenotypes in Arabidopsis.Plant & cell physiology · 2023Article
162 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Arabidopsis opr3 mutant is defective in the isoform of 12-oxo-phytodienoate (OPDA) reductase required for jasmonic acid (JA) biosynthesis. Oxylipin signatures of wounded opr3 leaves revealed the absence of detectable 3R,7S-JA as well as altered levels of its cyclopentenone precursors OPDA and dinor OPDA. In contrast to JA-insensitive coi1 plants and to the fad3 fad7 fad8 mutant lacking the fatty acid precursors of JA synthesis, opr3 plants exhibited strong resistance to the dipteran Bradysia impatiens and the fungus Alternaria brassicicola. Analysis of transcript profiles in opr3 showed the wound induction of genes previously known to be JA-dependent, suggesting that cyclopentenones could fulfill some JA roles in vivo. Treating opr3 plants with exogenous OPDA powerfully up-regulated several genes and disclosed two distinct downstream signal pathways, one through COI1, the other via an electrophile effect of the cyclopentenones. We conclude that the jasmonate family cyclopentenone OPDA (most likely together with dinor OPDA) regulates gene expression in concert with JA to fine-tune the expression of defense genes. More generally, resistance to insect and fungal attack can be observed in the absence of JA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.