ArticleChromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology2001
Absence of Z-chromosome inactivation for five genes in male chickens.
Article in Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 64 citations in OpenAlex.
- Screening and identification of genes for cell autonomous sex identity in chicken somatic cells.Poultry science · 2026Article
- Overview of Avian Sex Reversal.International journal of molecular sciences · 2023Review
- Transcriptomic and Epigenetic Preservation of Genetic Sex Identity in Estrogen-feminized Male Chicken Embryonic Gonads.Endocrinology · 2021Article
- Article
- Avian sex, sex chromosomes, and dosage compensation in the age of genomics.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2014Review
- Independent evolution of transcriptional inactivation on sex chromosomes in birds and mammals.PLoS genetics · 2013Article
- Genome-wide annotation and analysis of zebra finch microRNA repertoire reveal sex-biased expression.BMC genomics · 2012Article
- Possible differences in the two Z chromosomes in male chickens and evolution of MHM sequences in Galliformes.Chromosoma · 2011Article
- Sex bias and dosage compensation in the zebra finch versus chicken genomes: general and specialized patterns among birds.Genome research · 2010Article
- Activity map of the tammar X chromosome shows that marsupial X inactivation is incomplete and escape is stochastic.Genome biology · 2010Article
- Avian sex chromosomes: dosage compensation matters.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2009Article
- The status of dosage compensation in the multiple X chromosomes of the platypus.PLoS genetics · 2008Article
- Biased distributions and decay of long interspersed nuclear elements in the chicken genome.Genetics · 2008Article
- Faced with inequality: chicken do not have a general dosage compensation of sex-linked genes.BMC biology · 2007Article
- Dosage compensation is less effective in birds than in mammals.Journal of biology · 2007Article
- Regional differences in dosage compensation on the chicken Z chromosome.Genome biology · 2007Article
- Article
- Sex-dependent gene expression in early brain development of chicken embryos.BMC neuroscience · 2006Article
- Linkage mapping reveals sex-dimorphic map distances in a passerine bird.Proceedings. Biological sciences · 2005Article
- Sexually dimorphic expression of trkB, a Z-linked gene, in early posthatch zebra finch brain.Proceedings of the National Academy of Sciences of the United States of America · 2005Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In order to examine if Z-chromosome inactivation, which is analogous to X-chromosome inactivation in mammals, takes place in male birds having ZZ sex chromosomes, five Z-linked genes of chickens which are expressed in both sexes in certain tissues were selected: i.e. genes for growth hormone receptor, nicotinic acetylcholine receptor beta3, aldolase B, beta1,4-galactosyltransferase I, and iron-responsive element-binding protein (also known as cytosolic aconitase). Antisense or sense riboprobe was prepared from an intronic sequence of each gene and subjected to fluorescence in situ hybridization to nascent transcripts of each gene in a nucleus. Each antisense riboprobe hyridized to two spots of nascent RNA which corresponded to its gene loci on the two Z chromosomes in a majority of nuclei in a tissue of the male. The efficiency of detection of two spots per nucleus was comparable to that for the glyceraldehyde-3-phosphate dehydrogenase gene, an autosomal housekeeping gene. These results suggest strongly that Z-chromosome inactivation, i.e. virtual silence of transcription at one of the alleles, does not take place for these five Z-linked genes in male chickens.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.