ArticleThe Journal of cell biology2001
Functional characterization of the KNOLLE-interacting t-SNARE AtSNAP33 and its role in plant cytokinesis.
Article in The Journal of cell biology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
70 citing papers in PubMed, 176 citations in OpenAlex.
- Arabidopsis epigenetic factor AS2 mitigates nucleolar stress and promotes flat leaf development by repressing a CDK inhibitor.Development (Cambridge, England) · 2026Article
- Genome-Wide Identification and Characterization of Stress-Responsive SNARE Genes in Quinoa (Biology · 2026Article
- Cellular dynamics and molecular signaling networks of plant cytokinesis.Molecules and cells · 2026Review
- Article
- The Arabidopsis SNARE complex genes regulate the early stages of pollen-stigma interactions.Plant reproduction · 2024Article
- Roles of the ArabidopsisInternational journal of molecular sciences · 2024Article
- NSF/αSNAP2-mediated cis-SNARE complex disassembly precedes vesicle fusion in Arabidopsis cytokinesis.Nature plants · 2023Article
- Rab GTPases, tethers, and SNAREs work together to regulateFrontiers in plant science · 2023Review
- An interolog-based barley interactome as an integration framework for immune signaling.Genetics · 2022Article
- Cell biology of primary cell wall synthesis in plants.The Plant cell · 2022Review
- A rich and bountiful harvest: Key discoveries in plant cell biology.The Plant cell · 2022Review
- SNAREs Regulate Vesicle Trafficking During Root Growth and Development.Frontiers in plant science · 2022Review
- The Exocytosis Associated SNAP25-Type Protein, SlSNAP33, Increases Salt Stress Tolerance by Modulating Endocytosis in Tomato.Plants (Basel, Switzerland) · 2021Article
- SNAREs in Plant Biotic and Abiotic Stress Responses.Molecules and cells · 2020Review
- Functions of the Plant Qbc SNARE SNAP25 in Cytokinesis and Biotic and Abiotic Stress Responses.Molecules and cells · 2020Article
- Vesicle Transport in Plants: A Revised Phylogeny of SNARE Proteins.Evolutionary bioinformatics online · 2020Article
- OsSYP121 Accumulates at Fungal Penetration Sites and Mediates Host Resistance to Rice Blast.Plant physiology · 2019Article
- The Plant Trans-Golgi Network: Not Just a Matter of Distinction.Plant physiology · 2018Review
- GhSNAP33, a t-SNARE Protein FromFrontiers in plant science · 2018Article
- Activation of disease resistance againstHorticulture research · 2018Article
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cytokinesis requires membrane fusion during cleavage-furrow ingression in animals and cell plate formation in plants. In Arabidopsis, the Sec1 homologue KEULE (KEU) and the cytokinesis-specific syntaxin KNOLLE (KN) cooperate to promote vesicle fusion in the cell division plane. Here, we characterize AtSNAP33, an Arabidopsis homologue of the t-SNARE SNAP25, that was identified as a KN interactor in a yeast two-hybrid screen. AtSNAP33 is a ubiquitously expressed membrane-associated protein that accumulated at the plasma membrane and during cell division colocalized with KN at the forming cell plate. A T-DNA insertion in the AtSNAP33 gene caused loss of AtSNAP33 function, resulting in a lethal dwarf phenotype. atsnap33 plantlets gradually developed large necrotic lesions on cotyledons and rosette leaves, resembling pathogen-induced cellular responses, and eventually died before flowering. In addition, mutant seedlings displayed cytokinetic defects, and atsnap33 in combination with the cytokinesis mutant keu was embryo lethal. Analysis of the Arabidopsis genome revealed two further SNAP25-like proteins that also interacted with KN in the yeast two-hybrid assay. Our results suggest that AtSNAP33, the first SNAP25 homologue characterized in plants, is involved in diverse membrane fusion processes, including cell plate formation, and that AtSNAP33 function in cytokinesis may be replaced partially by other SNAP25 homologues.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.