ArticleGenome research2001
Chromosome-specific single-locus FISH probes allow anchorage of an 1800-marker integrated radiation-hybrid/linkage map of the domestic dog genome to all chromosomes.
Article in Genome research, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
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Who cites it
72 citing papers in PubMed, 281 citations in OpenAlex.
- The Initial Detection of Mycotoxins Released and Accumulated in the Golden Jackal (International journal of molecular sciences · 2025Article
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- Is increased mutation driving genetic diversity in dogs within the Chornobyl exclusion zone?PloS one · 2024Article
- White and other fur colourations and hybridization in golden jackals (Canis aureus) in the Carpathian basin.Scientific reports · 2023Article
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- Relationship of microsatellite instability to mismatch repair deficiency in malignant tumors of dogs.Journal of veterinary internal medicine · 2022Article
- Genetic diversity and mate selection in a reintroduced population of gray wolves.Scientific reports · 2022Article
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- First core microsatellite panel identification in Apennine brown bears (Ursus arctos marsicanus): a collaborative approach.BMC genomics · 2021Article
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- Automated genotyping of microsatellite loci from feces with high throughput sequences.PloS one · 2021Article
- Unraveling the mystery of the glacier bear: Genetic population structure of black bears (Ecology and evolution · 2020Article
- Phylogeography, genetic diversity, and connectivity of brown bear populations in Central Asia.PloS one · 2019Article
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- Intracoronary allogeneic cardiosphere-derived stem cells are safe for use in dogs with dilated cardiomyopathy.Journal of cellular and molecular medicine · 2017Article
- Microsatellite polymorphism and its association with body weight and selected morphometrics of farm red fox (Vulpes vulpes L.).Journal of applied genetics · 2014Article
- Population genetic structure of gray wolves (Canis lupus) in a marine archipelago suggests island-mainland differentiation consistent with dietary niche.BMC ecology · 2014Article
- Genetic connectivity for two bear species at wildlife crossing structures in Banff National Park.Proceedings. Biological sciences · 2014Article
- Canid hybridization: contemporary evolution in human-modified landscapes.Ecology and evolution · 2012Article
- Genetics of behavior in the silver fox.Mammalian genome : official journal of the International Mammalian Genome Society · 2012Review
12 more citing papers are in PubMed but not listed here.
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Authors and funding
24 authors at 1 institution in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We present here the first fully integrated, comprehensive map of the canine genome, incorporating detailed cytogenetic, radiation hybrid (RH), and meiotic information. We have mapped a collection of 266 chromosome-specific cosmid clones, each containing a microsatellite marker, to all 38 canine autosomes by fluorescence in situ hybridization (FISH). A 1500-marker RH map, comprising 1078 microsatellites, 320 dog gene markers, and 102 chromosome-specific markers, has been constructed using the RHDF5000-2 whole-genome radiation hybrid panel. Meiotic linkage analysis was performed, with at least one microsatellite marker from each dog autosome on a panel of reference families, allowing one meiotic linkage group to be anchored to all 38 dog autosomes. We present a karyotype in which each chromosome is identified by one meiotic linkage group and one or more RH groups. This updated integrated map, containing a total of 1800 markers, covers >90% of the dog genome. Positional selection of anchor clones enabled us, for the first time, to orientate nearly all of the integrated groups on each chromosome and to evaluate the extent of individual chromosome coverage in the integrated genome map. Finally, the inclusion of 320 dog genes into this integrated map enhances existing comparative mapping data between human and dog, and the 1000 mapped microsatellite markers constitute an invaluable tool with which to perform genome scanning studies on pedigrees of interest.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.