Coming to grips with Notch.

H von Boehmer

Abstract readComment

In one paragraph

Article in The Journal of experimental medicine, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it

0cells of the map it votes in

7citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

Notch signaling as an important mediator of cardiac repair and regeneration after myocardial infarction.Trends in cardiovascular medicine · 2010
Review
Activation of Notch-mediated protective signaling in the myocardium.Circulation research · 2008
Article
Regulation of lymphocyte development by cell-type-specific interpretation of Notch signals.Molecular and cellular biology · 2008
Article
Notch-induced E2A ubiquitination and degradation are controlled by MAP kinase activities.The EMBO journal · 2003
Article
The notch pathway: modulation of cell fate decisions in hematopoiesis.International journal of hematology · 2002
Review
Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2002
Article
Direct induction of T lymphocyte-specific gene expression by the mammalian Notch signaling pathway.Genes & development · 2002
Article

4 · The record

Corrections and comments

Comment on
Differential effects of Notch ligands Delta-1 and Jagged-1 in human lymphoid differentiation.2001
Comment on
Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus.2001

5 · Who and what money

Authors and funding

1 author.

H von BoehmerHarvard Medical School, Dana-Farber Cancer Institute, Boston, MA 02115, USA. harald_von_boehmer@dfci.harvard.edu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Carrier ProteinsTranscription FactorsAnimalsB-LymphocytesCell DifferentiationHumansIntracellular Signaling Peptides and ProteinsLigandsMembrane ProteinsModels, ImmunologicalProteinsReceptor, Notch1Receptors, Cell SurfaceReceptors, NotchSignal TransductionT-LymphocytesCarrier Proteinsdelta proteindeltex protein, vertebrateIntracellular Signaling Peptides and ProteinsLigandsMembrane ProteinsNOTCH1 protein, humanProteinsReceptor, Notch1Receptors, Cell SurfaceReceptors, NotchTranscription Factors

Identifiers

PMID11581323

DOI10.1084/jem.194.7.f43

PMCPMC2193486

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC-SA

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.