ArticleGenes & development2001
LAF1, a MYB transcription activator for phytochrome A signaling.
Article in Genes & development, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
74 citing papers in PubMed, 159 citations in OpenAlex.
- Twenty-five years of photobodies: formation, composition, and the 2-compartment logic of phytochrome B signaling.Plant physiology · 2026Review
- Transcriptomic analysis reveals light quality response and systemic nutrient allocation under monochromatic light environments in Nicotiana tabacum.BMC plant biology · 2025Article
- A multi-omic characterization of the physiological responses to salt stress in Scenedesmus obliquus UTEX393.Communications biology · 2025Article
- Light signaling as cellular integrator of multiple environmental cues in plants.Physiology and molecular biology of plants : an international journal of functional plant biology · 2023Review
- MYB112 connects light and circadian clock signals to promote hypocotyl elongation in Arabidopsis.The Plant cell · 2023Article
- Identification of the passion fruit (Frontiers in plant science · 2023Article
- EID1 promotes the response to canopy shade inmicroPublication biology · 2023Article
- Light-harvesting complex gene regulation by a MYB-family transcription factor in the marine diatom, Phaeodactylum tricornutum.Photosynthesis research · 2022Article
- Transposable element insertion: a hidden major source of domesticated phenotypic variation in Brassica rapa.Plant biotechnology journal · 2022Article
- Pivotal roles of ELONGATED HYPOCOTYL5 in regulation of plant development and fruit metabolism in tomato.Plant physiology · 2022Article
- Comprehensive analysis of 1R- and 2R-MYBs reveals novel genic and protein features, complex organisation, selective expansion and insights into evolutionary tendencies.Functional & integrative genomics · 2022Article
- Mutual upregulation of HY5 and TZP in mediating phytochrome A signaling.The Plant cell · 2022Article
- New insights into the response of maize to fluctuations in the light environment.Molecular genetics and genomics : MGG · 2021Article
- Article
- Specificity of MYB interactions relies on motifs in ordered and disordered contexts.Nucleic acids research · 2019Article
- Analysis of potential strategies for cadmium stress tolerance revealed by transcriptome analysis of upland cotton.Scientific reports · 2019Article
- Genome-Wide Characterization and Identification of Trihelix Transcription Factor and Expression Profiling in Response to Abiotic Stresses in Rice (International journal of molecular sciences · 2019Article
- The SUMO Conjugation Complex Self-Assembles into Nuclear Bodies Independent of SIZ1 and COP1.Plant physiology · 2019Article
- Article
- TANDEM ZINC-FINGER/PLUS3 Is a Key Component of Phytochrome A Signaling.The Plant cell · 2018Article
14 more citing papers are in PubMed but not listed here.
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
The photoreceptor phytochrome (phy) A has a well-defined role in regulating gene expression in response to specific light signals. Here, we describe a new Arabidopsis mutant, laf1 (long after far-red light 1) that has an elongated hypocotyl specifically under far-red light. Gene expression studies showed that laf1 has reduced responsiveness to continuous far-red light but retains wild-type responses to other light wavelengths. As far-red light is only perceived by phyA, our results suggest that LAF1 is specifically involved in phyA signal transduction. Further analyses revealed that laf1 is affected in a subset of phyA-dependent responses and the phenotype is more severe at low far-red fluence rates. LAF1 encodes a nuclear protein with strong homology with the R2R3-MYB family of DNA-binding proteins. Experiments using yeast cells identified a transactivation domain in the C-terminal portion of the protein. LAF1 is constitutively targeted to the nucleus by signals in its N-terminal portion, and the full-length protein accumulates in distinct nuclear speckles. This accumulation in speckles is abolished by a point mutation in a lysine residue (K258R), which might serve as a modification site by a small ubiquitin-like protein (SUMO).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.