Trial reportBMC neuroscience2001
Assessing the heritability of attentional networks.
Trial report in BMC neuroscience, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
92 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- "Give me a break!" A systematic review and meta-analysis on the efficacy of micro-breaks for increasing well-being and performance.PloS one · 2022Pooled it
- Candidate genes and neuropsychological phenotypes in children with ADHD: review of association studies.Journal of psychiatry & neuroscience : JPN · 2009Pooled it
- A Pilot Study Examining the Effects of Music Training on Attention in Children with Fetal Alcohol Spectrum Disorders (FASD).Sensors (Basel, Switzerland) · 2022Trial
- A Neurofunctional Domains Approach to Evaluate D1/D5 Dopamine Receptor Partial Agonism on Cognition and Motivation in Healthy Volunteers With Low Working Memory Capacity.The international journal of neuropsychopharmacology · 2020Trial
- Double-Blind, Sham-Controlled, Pilot Study of Trigeminal Nerve Stimulation for Attention-Deficit/Hyperactivity Disorder.Journal of the American Academy of Child and Adolescent Psychiatry · 2019Trial
- Assessing the molecular genetics of attention networks.BMC neuroscience · 2002Trial
- Individual differences in brain attention networks: the challenge of indexing temporal change.Frontiers in cognition · 2025Article
- Characterizing the functioning of the attentional networks in state and trait anxiety: the role of affective information.Frontiers in psychology · 2025Article
- Improving accuracy and precision of heritability estimation in twin studies through hierarchical modeling: reassessing the measurement error assumption.Frontiers in genetics · 2025Article
- Effects of Background Music on Attentional Networks of Children With and Without Attention Deficit/Hyperactivity Disorder: Case Control Experimental Study.Interactive journal of medical research · 2024Article
- Molecular signatures of attention networks.Human brain mapping · 2024Article
- Heritability of cognitive and emotion processing during functional MRI in a twin sample.Human brain mapping · 2024Article
- Cognitive impairment in Chinese adult patients with type III spinal muscular atrophy without disease-modifying treatment.Frontiers in neurology · 2023Article
- Attention networks and the intrinsic network structure of the human brain.Human brain mapping · 2022Article
- A Pilot Study Testing the Effectiveness of a Mindfulness-Based Program for Portuguese School Children.Mindfulness · 2022Article
- CyberGenomics: Application of Behavioral Genetics in Cybersecurity.Behavioral sciences (Basel, Switzerland) · 2021Review
- Gender Differences in Attention Adaptation after an 8-Week FIFA 11Children (Basel, Switzerland) · 2021Article
- Two separate, large cohorts reveal potential modifiers of age-associated variation in visual reaction time performance.NPJ aging and mechanisms of disease · 2021Article
- Measuring attention and vigilance in the laboratory vs. online: The split-half reliability of the ANTI-Vea.Behavior research methods · 2021Article
- Evaluating endophenotypes for bipolar disorder.International journal of bipolar disorders · 2021Review
32 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCurrent efforts to study the genetics of higher functions have been lacking appropriate phenotypes to describe cognition. One of the problems is that many cognitive concepts for which there is a single word (e.g. attention) have been shown to be related to several anatomical networks. Recently we have developed an Attention Network Test (ANT) that provides a separate measure for each of three anatomically defined attention networks. In this small scale study, we ran 26 pairs of MZ and DZ twins in an effort to determine if any of these networks show sufficient evidence of heritability to warrant further exploration of their genetic basis.
resultsThe efficiency of the executive attention network, that mediates stimulus and response conflict, shows sufficient heritability to warrant further study. Alerting and overall reaction time show some evidence for heritability and in our study the orienting network shows no evidence of heritability.
conclusionsThese results suggest that genetic variation contributes to normal individual differences in higher order executive attention involving dopamine rich frontal areas including the anterior cingulate. At least the executive portion of the ANT may serve as a valid endophenotype for larger twin studies and subsequent molecular genetic analysis in normal subject populations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.