ReviewAmerican journal of human genetics2001
At the speed of sound: gene discovery in the auditory system.
Review in American journal of human genetics, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Genetics Evaluation Guidelines for the Etiologic Diagnosis of Congenital Hearing Loss. Genetic Evaluation of Congenital Hearing Loss Expert Panel. ACMG statement.Genetics in medicine : official journal of the American College of Medical GeneticsGuideline
- Research Advances on Deafness Genes Associated with Mitochondrial tRNA-37 Modifications.The journal of international advanced otology · 2023Review
- Targeted Next-Generation Sequencing of a Deafness Gene Panel (MiamiOtoGenes) Analysis in Families Unsuitable for Linkage Analysis.BioMed research international · 2018Article
- Mutations of TMC1 cause deafness by disrupting mechanoelectrical transduction.Auris, nasus, larynx · 2014Article
- An acoustic gap between the NICU and womb: a potential risk for compromised neuroplasticity of the auditory system in preterm infants.Frontiers in neuroscience · 2014Article
- Extracellular gentamicin reduces the activity of connexin hemichannels and interferes with purinergic Ca(2+) signaling in HeLa cells.Frontiers in cellular neuroscience · 2014Article
- Diagnostic application of targeted resequencing for familial nonsyndromic hearing loss.PloS one · 2013Article
- Expression of deafness protein Tmie in postnatal developmental stages of C57BL/6J mice.Laboratory animal research · 2012Article
- Genetic mutations in non-syndromic deafness patients of Uyghur and Han Chinese ethnicities in Xinjiang, China: a comparative study.Journal of translational medicine · 2011Article
- Functional mutation of SMAC/DIABLO, encoding a mitochondrial proapoptotic protein, causes human progressive hearing loss DFNA64.American journal of human genetics · 2011Article
- Absence of GJB2 gene mutations, the GJB6 deletion (GJB6-D13S1830) and four common mitochondrial mutations in nonsyndromic genetic hearing loss in a South African population.International journal of pediatric otorhinolaryngology · 2011Article
- Identification of candidate regions for a novel Usher syndrome type II locus.Molecular vision · 2008Article
- DFNB48, a new nonsyndromic recessive deafness locus, maps to chromosome 15q23-q25.1.Human genetics · 2005Article
- DFNB39, a recessive form of sensorineural hearing impairment, maps to chromosome 7q11.22-q21.12.European journal of human genetics : EJHG · 2003Article
- Genetic linkage analysis of a novel syndrome comprising North Carolina-like macular dystrophy and progressive sensorineural hearing loss.The British journal of ophthalmology · 2003Article
- Gene structure, chromosomal localization, and mutation screening of the human gene for the inner ear protein otospiralin.Neurogenetics · 2003Article
- A second kindred linked to DFNA20 (17q25.3) reduces the genetic interval.Clinical genetics · 2003Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As auditory genes and deafness-associated mutations are discovered at a rapid rate, exciting opportunities have arisen to uncover the molecular mechanisms underlying hearing and hearing impairment. Single genes have been identified to be pathogenic for dominant or recessive forms of nonsyndromic hearing loss, syndromic hearing loss, and, in some cases, even multiple forms of hearing loss. Modifier loci and genes have been found, and investigations into their role in the hearing process will yield valuable insight into the fundamental processes of the auditory system.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.