Evidence map›Paper›PMID 11577168›Full record

ReviewMolecular pathology : MP2001

IGFs and IGFBPs: surrogate markers for diagnosis and surveillance of tumour growth?

W Zumkeller

Open access · bronzeAbstract readReview
In one paragraph

Review in Molecular pathology : MP, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 43 citations in OpenAlex.

  1. Trial
  2. Tumors overcome the action of the wasting factor ImpL2 by locally elevating Wnt/Wingless.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  3. Article
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  6. Anti-inflammatory activity of soy and tea in prostate cancer prevention.Experimental biology and medicine (Maywood, N.J.) · 2010
    Article
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  8. Article
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  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

W ZumkellerDepartment of Paediatrics, Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Str. 40, 06097 Halle/Saale, Germany. walter.zumkeller@medizin.uni-halle.de
Martin Luther University Halle-Wittenberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Insulin-like growth factors (IGFs), IGF receptors, and IGF binding proteins (IGFBPs) constitute the IGF system. Comprehensive data indicate that these factors play a pivotal role in tumorigenesis. Epidemiological data indicate that cancer risk is associated with high serum IGF-I values. Because dysregulation of the IGF system is a frequent pattern in malignancy, IGFs/IGFBPs might represent novel tumour markers that could be useful both for diagnosis and surveillance.

Indexed as

AnimalsBiomarkers, TumorBreast NeoplasmsColorectal NeoplasmsFemaleHumansInsulin-Like Growth Factor Binding ProteinsInsulin-Like Growth Factor IInsulin-Like Growth Factor IIMaleMiceMice, TransgenicProstatic NeoplasmsRatsReceptor, IGF Type 1Receptor, IGF Type 2Biomarkers, TumorInsulin-Like Growth Factor Binding ProteinsInsulin-Like Growth Factor IInsulin-Like Growth Factor IIReceptor, IGF Type 1Receptor, IGF Type 2

Identifiers

PMID11577168
PMCPMC1187083
OpenAlexW1965651128

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.