ArticleProceedings of the National Academy of Sciences of the United States of America2001
Fine-scale mapping of a locus for severe bipolar mood disorder on chromosome 18p11.3 in the Costa Rican population.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 38 citations in OpenAlex.
- Progress and Implications from Genetic Studies of Bipolar Disorder.Neuroscience bulletin · 2024Review
- Understanding the Hidden Complexity of Latin American Population Isolates.American journal of human genetics · 2018Article
- Modeling mania in preclinical settings: A comprehensive review.Progress in neuro-psychopharmacology & biological psychiatry · 2016Review
- Summaries of plenary, symposia, and oral sessions at the XXII World Congress of Psychiatric Genetics, Copenhagen, Denmark, 12-16 October 2014.Psychiatric genetics · 2016Article
- Neuropsychological and dimensional behavioral trait profiles in Costa Rican ADHD sib pairs: Potential intermediate phenotypes for genetic studies.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2015Article
- Comprehensive behavioral analysis of pituitary adenylate cyclase-activating polypeptide (PACAP) knockout mice.Frontiers in behavioral neuroscience · 2012Article
- Identification of novel schizophrenia loci by homozygosity mapping using DNA microarray analysis.PloS one · 2011Article
- Association study on the mitochondrial gene NDUFV2 and bipolar disorder in the Chinese Han population.Journal of neural transmission (Vienna, Austria : 1996) · 2009Article
- Polymorphisms of the IGF1R gene and their genetic effects on chicken early growth and carcass traits.BMC genetics · 2008Article
- Genetics of bipolar disorder.Dialogues in clinical neuroscience · 2008Review
- TGFB-induced factor (TGIF): a candidate gene for psychosis on chromosome 18p.Molecular psychiatry · 2007Article
- Dense SNP association study for bipolar I disorder on chromosome 18p11 suggests two loci with excess paternal transmission.Molecular psychiatry · 2007Article
- Genomewide linkage scan for bipolar-disorder susceptibility loci among Ashkenazi Jewish families.American journal of human genetics · 2004Article
- Trapping and sequence analysis of 1138 putative exons from human chromosome 18.Molecular psychiatry · 2003Article
Corrections and comments
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Authors and funding
35 authors at 1 institution in 1 country.
Funding
Abstract
We have searched for genes predisposing to bipolar disorder (BP) by studying individuals with the most extreme form of the affected phenotype, BP-I, ascertained from the genetically isolated population of the Central Valley of Costa Rica (CVCR). The results of a previous linkage analysis on two extended CVCR BP-I pedigrees, CR001 and CR004, and of linkage disequilibrium (LD) analyses of a CVCR population sample of BP-I patients implicated a candidate region on 18p11.3. We further investigated this region by creating a physical map and developing 4 new microsatellite and 26 single-nucleotide polymorphism markers for typing in the pedigree and population samples. We report the results of fine-scale association analyses in the population sample, as well as evaluation of haplotypes in pedigree CR001. Our results suggest a candidate region containing six genes but also highlight the complexities of LD mapping of common disorders.
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