ArticleApplied and environmental microbiology2001
Determination of pyrimidine dimers in Escherichia coli and Cryptosporidium parvum during UV light inactivation, photoreactivation, and dark repair.
Article in Applied and environmental microbiology, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 178 citations in OpenAlex.
- UV-C LED wavelength effects on inactivation kinetics, DNA damage and membrane integrity in drinking water indicator bacteria.Scientific reports · 2026Article
- Efficacy of ultraviolet-light emitting diodes in bacterial inactivation and DNA damage via sensitivity evaluation using multiple wavelengths and bacterial strains.Archives of microbiology · 2025Article
- Ultraviolet C inactivation of Coxiella burnetii for production of a structurally preserved whole cell vaccine antigen.BMC microbiology · 2024Article
- Exploring a chemical scaffold for rapid and selective photoaffinity labelling of non-ribosomal peptide synthetases in living bacterial cells.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Article
- Wind of change: Better air for microbial environmental control.Case studies in chemical and environmental engineering · 2022Article
- Effectiveness of solar water disinfection in the era of COVID-19 (SARS-CoV-2) pandemic for contaminated water/wastewater treatment considering UV effect and temperature.Journal of water process engineering · 2021Article
- Impact of a Combination of UV-C Irradiation and Peracetic Acid Spray Treatment onFoods (Basel, Switzerland) · 2021Article
- Sensitivity of Bacteria, Protozoa, Viruses, and Other Microorganisms to Ultraviolet Radiation.Journal of research of the National Institute of Standards and Technology · 2021Article
- Disinfection of Wastewater by UV-Based Treatment for Reuse in a Circular Economy Perspective. Where Are We at?International journal of environmental research and public health · 2020Review
- Simplified modeling of E. coli mortality after genome damage induced by UV-C light exposure.Scientific reports · 2020Article
- Article
- Oral inoculation of ultraviolet-irradiated Eimeria species oocysts protects chickens against coccidiosis.Parasitology research · 2019Article
- Activated Carbon as a Cathode for Water Disinfection through the Electro-Fenton Process.Catalysts (Basel, Switzerland) · 2019Article
- Mixture of Sodium Hypochlorite and Hydrogen Peroxide on Adhered Aeromonas hydrophila to Solid Substrate in Water: Impact of Concentration and Assessment of the Synergistic Effect.International journal of bacteriology · 2014Article
- The nucleotide excision repair system of Borrelia burgdorferi is the sole pathway involved in repair of DNA damage by UV light.Journal of bacteriology · 2013Article
- Solar radiation induces non-nuclear perturbations and a false start to regulated exocytosis in Cryptosporidium parvum.PloS one · 2010Article
- Stress-induced Hsp70 gene expression and inactivation of Cryptosporidium parvum oocysts by chlorine-based oxidants.Applied and environmental microbiology · 2010Article
- Indicators for photoreactivation and dark repair studies following ultraviolet disinfection.Journal of industrial microbiology & biotechnology · 2008Article
- Effects of UV radiation on photolyase and implications with regards to photoreactivation following low- and medium-pressure UV disinfection.Applied and environmental microbiology · 2008Article
- Detection of UV-induced thymine dimers in individual Cryptosporidium parvum and Cryptosporidium hominis oocysts by immunofluorescence microscopy.Applied and environmental microbiology · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
UV inactivation, photoreactivation, and dark repair of Escherichia coli and Cryptosporidium parvum were investigated with the endonuclease sensitive site (ESS) assay, which can determine UV-induced pyrimidine dimers in the genomic DNA of microorganisms. In a 99.9% inactivation of E. coli, high correlation was observed between the dose of UV irradiation and the number of pyrimidine dimers induced in the DNA of E. coli. The colony-forming ability of E. coli also correlated highly with the number of pyrimidine dimers in the DNA, indicating that the ESS assay is comparable to the method conventionally used to measure colony-forming ability. When E. coli were exposed to fluorescent light after a 99.9% inactivation by UV irradiation, UV-induced pyrimidine dimers in the DNA were continuously repaired and the colony-forming ability recovered gradually. When kept in darkness after the UV inactivation, however, E. coli showed neither repair of pyrimidine dimers nor recovery of colony-forming ability. When C. parvum were exposed to fluorescent light after UV inactivation, UV-induced pyrimidine dimers in the DNA were continuously repaired, while no recovery of animal infectivity was observed. When kept in darkness after UV inactivation, C. parvum also showed no recovery of infectivity in spite of the repair of pyrimidine dimers. It was suggested, therefore, that the infectivity of C. parvum would not recover either by photoreactivation or by dark repair even after the repair of pyrimidine dimers in the genomic DNA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.