ArticleArchives of disease in childhood2001
Fine needle aspiration biopsy of thyroid nodules.
Article in Archives of disease in childhood, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 81 citations in OpenAlex.
- Papillary thyroid carcinoma in an 8-year-old Ethiopian child: A case report with literature review.SAGE open medical case reports · 2024Article
- The Clinical and Pathological Presentation of Thyroid Nodules in Children and the Comparison with Adult Population: Experience of a Single Institution.International journal of endocrinology · 2016Article
- Evaluation and management of the pediatric thyroid nodule.The oncologist · 2015Review
- Efficacy and Pitfalls of FNAC of Thyroid Lesions in Children and Adolescents.Journal of clinical and diagnostic research : JCDR · 2014Article
- Fine needle aspiration: an atraumatic method to diagnose head and neck masses.Trauma monthly · 2013Article
- Needle core biopsy in the diagnosis of pediatric thyroid neoplasms: a single institution retrospective review.Pediatric surgery international · 2013Article
- Combination of aspiration and non-aspiration fine needle biopsy for cytological diagnosis of thyroid nodules.Caspian journal of internal medicine · 2011Article
- Diagnostic utility of fine-needle aspiration cytology in pediatric differentiated thyroid cancer.World journal of surgery · 2010Article
- Thyroid nodules in childhood: a single institute experience.Iranian journal of pediatrics · 2010Article
- Fine-needle aspiration biopsy in the diagnosis and follow-up of thyroid nodules in childhood.Journal of clinical research in pediatric endocrinology · 2010Article
- Thyroid fine needle aspiration biopsies in children: study of cytological-histological correlation and immunostaining with thyroid peroxidase monoclonal antibodies.International journal of pediatric endocrinology · 2010Article
- A comparative study of fine needle aspiration and fine needle non-aspiration biopsy on suspected thyroid nodules.Endocrine pathology · 2009Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFine needle aspiration biopsy (FNA) is a routine diagnostic technique for evaluating thyroid nodules. Many reports in adults consider that FNA is superior to thyroid ultrasonography (USG) and radionuclide scanning (RS). Only five studies have been published on FNA of childhood thyroid nodules.
aimsTo investigate the reliability of FNA in the evaluation and management of thyroid nodules, and compare the results of FNA, USG, and RS with regard to final histopathological diagnosis.
methodsFNA was performed in 46 children with thyroid nodules after USG and RS examination. We investigated the sensitivity, specificity, accuracy, and positive and negative predictive values of USG, RS, and FNA in their management.
resultsSix patients who had malignant or suspicious cells on FNA examination underwent immediate surgery. The other 40 patients received medical treatment according to their hormonal status. Fifteen of these nodules either disappeared or decreased in number and/or size. Surgery was performed in 25 patients who did not respond to therapy. Statistical analysis revealed sensitivity, specificity, accuracy, and positive and negative predictive values respectively as follows: 60%, 59%, 59%, 15%, and 92% for USG; 30%, 42%, 39%, 12%, and 68% for SC; 100%, 95%, 95%, 67%, and 100% for FNAB.
conclusionFNAB is as reliable in children as in adults for definitive diagnosis of thyroid nodules. Using this technique avoids unnecessary thyroid surgery in children.
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