Evidence map›Paper›PMID 11566828›Full record

Trial reportBMJ (Clinical research ed.)2001

Is voice therapy an effective treatment for dysphonia? A randomised controlled trial.

K MacKenzie, A Millar, J A Wilson, C Sellars, I J Deary

Registry-linked trialAbstract readClinical TrialRandomized Controlled Trial
In one paragraph

Trial report in BMJ (Clinical research ed.), 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02409758 (The Effectiveness of the Comprehensive Voice Rehabilitation Program Compared With Vocal Function Exercises Method in Behavioral Dysphonia), which is not on this map. Cited by 27 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02409758 early_phase1completednot on this mapstarted 2011, after this paper: background citation

The Effectiveness of the Comprehensive Voice Rehabilitation Program Compared With Vocal Function Exercises Method in Behavioral Dysphonia: A Randomized Controlled Clinical Trial.

TypeinterventionalSponsorFederal University of São PauloRan2011 to 2012Enrolled106ConditionsDysphoniaArmsVoice therapy
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Dystonia rating scales: critique and recommendations.Movement disorders : official journal of the Movement Disorder Society · 2013
    Pooled it
  3. Interventions for preventing voice disorders in adults.The Cochrane database of systematic reviews · 2007
    Pooled it
  4. Interventions for treating functional dysphonia in adults.The Cochrane database of systematic reviews · 2007
    Pooled it
  5. The Role of Oral Steroids in the Treatment of Phonotraumatic Vocal Fold Lesions in Women.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2019
    Trial
  6. Trial
  7. Dysphonia: medical treatment and a medical voice hygiene advice approach. A prospective randomised pilot study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2004
    Trial
  8. Effectiveness of Teletherapy in Managing Voice Disorders: A Systematic Review.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
    Article
  9. Review
  10. Review
  11. Examining Therapy Duration in Adults With Voice Disorders.American journal of speech-language pathology · 2023
    Observational
  12. Article
  13. Article
  14. Article
  15. Factors Influencing Likelihood of Voice Therapy Attendance.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2017
    Article
  16. Hoarseness-causes and treatments.Deutsches Arzteblatt international · 2015
    Review
  17. Psychosocial distress in patients presenting with voice concerns.Journal of voice : official journal of the Voice Foundation · 2014
    Article
  18. Article
  19. Treatment for spasmodic dysphonia: limitations of current approaches.Current opinion in otolaryngology & head and neck surgery · 2009
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

K MacKenzieDepartment of Otorhinolaryngology and Head and Neck Surgery, Glasgow Royal Infirmary, Glasgow G31 2ER. kmk2x@clinm,ed.gla.ac.uk
A Millar
J A Wilson
C Sellars
I J Deary

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the overall efficacy of voice therapy for dysphonia.

designSingle blind randomised controlled trial.

settingOutpatient clinic in a teaching hospital.

participants204 outpatients aged 17-87 with a primary symptom of persistent hoarseness for at least two months.

interventionsAfter baseline assessments, patients were randomised to six weeks of either voice therapy or no treatment. Assessments were repeated at six weeks on the 145 (71%) patients who continued to this stage and at 12-14 weeks on the 133 (65%) patients who completed the study. The assessments at the three time points for the 70 patients who completed treatment and the 63 patients in the group given no treatment were compared.

main outcome measuresRatings of laryngeal features, Buffalo voice profile, amplitude and pitch perturbation, voice profile questionnaire, hospital anxiety and depression scale, clinical interview schedule, SF-36.

resultsVoice therapy improved voice quality as assessed by rating by patients (P=0.001) and rating by observer (P<0.001). The treatment effects for these two outcomes were 4.1 (95% confidence interval 1.7 to 6.6) points and 0.82 (0.50 to 1.13) points. Amplitude perturbation showed improvement at six weeks (P=0.005) but not on completion of the study. Patients with dysphonia had appreciable psychological distress and lower quality of life than controls, but voice therapy had no significant impact on either of these variables.

conclusionVoice therapy is effective in improving voice quality as assessed by self rated and observer rated methods.

Indexed as

Voice TrainingAdolescentAdultAgedAnxiety DisordersDepressive DisorderFemaleFollow-Up StudiesHumansMaleMiddle AgedQuality of LifeSingle-Blind MethodTreatment OutcomeVoice DisordersVoice Quality

Identifiers

PMID11566828
PMCPMC55924

What OpenQuestion holds

Textmetadata
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.